Blepharitis in the United States 2009: A Survey-based Perspective on Prevalence and Treatment

被引:181
作者
Lemp, Michael A. [1 ]
Nichols, Kelly K. [2 ]
机构
[1] George Washington Univ, Dept Ophthalmol, Sch Med, Washington, DC 20052 USA
[2] Ohio State Univ, Coll Optometry, Columbus, OH 43210 USA
关键词
Blepharitis; anterior blepharitis; posterior blepharitis; meibomian gland; dry eye disease; prevalence; ocular surface disease; MEIBOMIAN GLAND DYSFUNCTION; DRY EYE; MANAGEMENT; DIAGNOSIS; DISEASE;
D O I
10.1016/S1542-0124(12)70620-1
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Like dry eye disease 15 years ago, blepharitis today is a poorly defined condition about which there is considerable misunderstanding. For a variety of reasons, there is little good data on either the prevalence of blepharitis or how eyecare practitioners currently treat it. The work reported herein consists of two recent studies: a telephone survey of a representative sample of the adult US population (n = 5,000) whose purpose was to discover the frequency of common ocular surface symptoms associated with blepharitis; and a study that queried a selected group of ophthalmologists (n = 120) and a similarly selected group of optometrists (n = 84) about the frequency of blepharitis in their practices, the existence comorbid conditions, and their management strategies. This data suggests that blepharitis symptoms are very common in the US population, with younger individuals reporting more, and more frequent, symptoms than older people, contrary to clinical dogma. Ophthalmologists and optometrists report that blepharitis is commonly seen in clinical practice in 37% and 47% of their patients, respectively, and it is widely agreed that meibomian gland dysfunction (MGD) is the most common cause of evaporative dry eye disease. In addition, management paradigms are shifting away from more traditional management with antibiotic ointment and warm compress therapy to prescription therapy for anterior and posterior blepharitis.
引用
收藏
页码:S1 / S14
页数:14
相关论文
共 26 条
[1]  
AYLIFFE W, 2004, SMOLIN THOFTS CORNEA, P647
[2]   Responses of contact lens wearers to a dry eye survey [J].
Begley, CG ;
Caffery, B ;
Nichols, KK ;
Chalmers, R .
OPTOMETRY AND VISION SCIENCE, 2000, 77 (01) :40-46
[3]   Dysfunctional tear syndrome - A Delphi approach to treatment recommendations [J].
Behrens, Ashley ;
Doyle, John J. ;
Stern, Lee ;
Chuck, Roy S. ;
McDonnell, Peter J. ;
Azar, Dimitri T. ;
Dua, Harminder S. ;
Hom, Milton ;
Karpecki, Paul M. ;
Laibson, Peter R. ;
Lemp, Michael A. ;
Meisler, David M. ;
Murube del Castillo, Juan ;
O'Brien, Terrence P. ;
Pflugfelder, Stephen C. ;
Rolando, Maurizio ;
Schein, Oliver D. ;
Seitz, Berthold ;
Tseng, Scheffer C. ;
van Setten, Gysbert ;
Wilson, Steven E. ;
Yiu, Samuel C. .
CORNEA, 2006, 25 (08) :900-907
[4]  
Bron A J, 2004, Ocul Surf, V2, P149
[5]  
Campbell Alliance Group, 2008, PATT PRACT PREV RAT
[6]  
Chalmers Robin L, 2006, Cont Lens Anterior Eye, V29, P25, DOI 10.1016/j.clae.2005.12.004
[7]  
Christen W G, 1998, Ophthalmic Epidemiol, V5, P133, DOI 10.1076/opep.5.3.133.8368
[8]   Design of physicians' health study II - A randomized trial of beta-carotene, vitamins E and C, and multivitamins, in prevention of cancer, cardiovascular disease, and eye disease, and review of results of completed trials [J].
Christen, WG ;
Gaziano, JM ;
Hennekens, CH .
ANNALS OF EPIDEMIOLOGY, 2000, 10 (02) :125-134
[9]   Meibomian gland dysfunction [J].
Driver, PJ ;
Lemp, MA .
SURVEY OF OPHTHALMOLOGY, 1996, 40 (05) :343-367
[10]   DEWS report: A mission completed [J].
Foulks, Gary N. .
OCULAR SURFACE, 2007, 5 (02) :65-66