Soluble Guanylate Cyclase Not a Dull Enzyme

被引：15

作者：

Boerrigter, Guido

Burnett, John C., Jr.

机构：

[1] Mayo Clin, Coll Med, Cardiorenal Res Lab, Div Cardiovasc Dis,Dept Med, Rochester, MN USA

[2] Mayo Clin, Coll Med, Cardiorenal Res Lab, Div Cardiovasc Dis,Dept Physiol, Rochester, MN USA

来源：

CIRCULATION | 2009年 / 119卷 / 21期

关键词：

Editorials; heart failure; nitric oxide; pharmacology; vasculature; vasodilation; CONGESTIVE-HEART-FAILURE; INDEPENDENT ACTIVATION; HEME; NITROGLYCERIN; NESIRITIDE; BINDING;

D O I：

10.1161/CIRCULATIONAHA.109.860288

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

引用

页码：2752 / 2754

页数：3

共 20 条

[1]

Cardiorenal and humoral properties of a novel direct soluble guanylate cyclase stimulator BAY 41-2272 in experimental congestive heart failure [J].

Boerrigter, G ;

Costello-Boerrigter, LC ;

Cataliotti, A ;

Tsuruda, T ;

Harty, GJ ;

Lapp, H ;

Stasch, JP ;

Burnett, JC .

CIRCULATION, 2003, 107 (05) :686-689

[2]

Targeting heme-oxidized soluble guanylate cyclase in experimental heart failure [J].

Boerrigter, Guido ;

Costello-Boerrigter, Lisa C. ;

Cataliotti, Alessandro ;

Lapp, Harald ;

Stasch, Johannes-Peter ;

Burnett, John C., Jr. .

HYPERTENSION, 2007, 49 (05) :1128-1133

[3]

Brunton T.L., 1867, LANCET, Vii, P97, DOI DOI 10.1016/S0140-6736(02)51392-1

[4]

Pharmacokinetics, Pharmacodynamics, Tolerability, and Safety of the Soluble Guanylate Cyclase Activator Cinaciguat (BAY 58-2667) in Healthy Male Volunteers [J].

Frey, Reiner ;

Mueck, Wolfgang ;

Unger, Sigrun ;

Artmeier-Brandt, Ulrike ;

Weimann, Gerrit ;

Wensing, Georg .

JOURNAL OF CLINICAL PHARMACOLOGY, 2008, 48 (12) :1400-1410

[5]

First acute haemodynamic study of soluble guanylate cyclase stimulator riociguat in pulmonary hypertension [J].

Grimminger, F. ;

Weimann, G. ;

Frey, R. ;

Voswinckel, R. ;

Thamm, M. ;

Boelkow, D. ;

Weissmann, N. ;

Mueck, W. ;

Unger, S. ;

Wensing, G. ;

Schermuly, R. T. ;

Ghofrani, H. A. .

EUROPEAN RESPIRATORY JOURNAL, 2009, 33 (04) :785-792

[6]

ACTIVATION OF PURIFIED SOLUBLE GUANYLATE-CYCLASE BY PROTOPORPHYRIN-IX [J].

IGNARRO, LJ ;

WOOD, KS ;

WOLIN, MS .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (09) :2870-2873

[7]

YC-1, A NOVEL ACTIVATOR OF PLATELET GUANYLATE-CYCLASE [J].

KO, FN ;

WU, CC ;

KUO, SC ;

LEE, FY ;

TENG, CM .

BLOOD, 1994, 84 (12) :4226-4233

[8]

Kornberg A., 1989, For the love of enzymes: the odyssey of a biochemist

[9]

Cinaciguat (BAY 58-2667) Improves Cardiopulmonary Hemodynamics in Patients With Acute Decompensated Heart Failure [J].

Lapp, Harald ;

Mitrovic, Veselin ;

Franz, Norbert ;

Heuer, Hubertus ;

Buerke, Michael ;

Wolfertz, Judith ;

Mueck, Wolfgang ;

Unger, Sigrun ;

Wensing, Georg ;

Frey, Reiner .

CIRCULATION, 2009, 119 (21) :2781-2788

[10]

Probing the presence of the ligand-binding haem in cellular nitric oxide receptors [J].

Roy, B. ;

Mo, E. ;

Vernon, J. ;

Garthwaite, J. .

BRITISH JOURNAL OF PHARMACOLOGY, 2008, 153 (07) :1495-1504

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