The multifunctional, multi-institutional, and sometimes even global phase I study: A better life for phase I evaluations or just "living large"?

被引：9

作者：

Tolcher, AW ^{[1
]}

Takimoto, CH ^{[1
]}

Rowinsky, EK ^{[1
]}

机构：

[1] Univ Texas, Hlth Sci Ctr, Inst Drug Dev, Canc Therapy & Res Ctr, San Antonio, TX USA

来源：

JOURNAL OF CLINICAL ONCOLOGY | 2002年 / 20卷 / 21期

关键词：

D O I：

10.1200/JCO.2002.20.21.4276

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

引用

页码：4276 / 4278

页数：3

共 15 条

[1]

Phase I safety, pharmacokinetic, and pharmacodynamic trial of ZD1839, a selective oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with five selected solid tumor types [J].

Baselga, J ;

Rischin, D ;

Ranson, M ;

Calvert, H ;

Raymond, E ;

Kieback, DG ;

Kaye, SB ;

Gianni, L ;

Harris, A ;

Bjork, T ;

Averbuch, SD ;

Feyereislova, A ;

Swaisland, H ;

Rojo, F ;

Albanell, J .

JOURNAL OF CLINICAL ONCOLOGY, 2002, 20 (21) :4292-4302

[2]

Cohen MH, 2002, CLIN CANCER RES, V8, P935

[3]

DOCETAXEL [J].

CORTES, JE ;

PAZDUR, R .

JOURNAL OF CLINICAL ONCOLOGY, 1995, 13 (10) :2643-2655

[4]

DUDLEY HAF, 1968, LANCET, V2, P723

[5]

ASSESSMENT OF A PATTERN-RECOGNITION EXAMINATION IN A CLINICAL CLERKSHIP [J].

DUNN, MM ;

WOOLLISCROFT, JO .

ACADEMIC MEDICINE, 1994, 69 (08) :683-684

[6]

Friedrich MJ, 2002, J NATL CANCER I, V94, P650

[7]

PRIMARY KNOWLEDGE, MEDICAL-EDUCATION AND CONSULTANT EXPERTISE [J].

GRANT, J ;

MARSDEN, P .

MEDICAL EDUCATION, 1988, 22 (03) :173-179

[8]

Phase I and pharmacologic study of OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in patients with advanced solid malignancies [J].

Hidalgo, M ;

Siu, LL ;

Nemunaitis, J ;

Rizzo, J ;

Hammond, LA ;

Takimoto, C ;

Eckhardt, SG ;

Tolcher, A ;

Britten, CD ;

Denis, L ;

Ferrante, K ;

Von Hoff, DD ;

Silberman, S ;

Rowinsky, EK .

JOURNAL OF CLINICAL ONCOLOGY, 2001, 19 (13) :3267-3279

[9]

CONTINUAL REASSESSMENT METHOD - A PRACTICAL DESIGN FOR PHASE-1 CLINICAL-TRIALS IN CANCER [J].

OQUIGLEY, J ;

PEPE, M ;

FISHER, L .

BIOMETRICS, 1990, 46 (01) :33-48

[10]

SUCCESSFUL RETREATMENT WITH TAXOL AFTER MAJOR HYPERSENSITIVITY REACTIONS [J].

PEEREBOOM, DM ;

DONEHOWER, RC ;

EISENHAUER, EA ;

MCGUIRE, WP ;

ONETTO, N ;

HUBBARD, JL ;

PICCART, M ;

GIANNI, L ;

ROWINSKY, EK .

JOURNAL OF CLINICAL ONCOLOGY, 1993, 11 (05) :885-890

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