Sequence similarities between human bornavirus isolates and laboratory strains question human origin

被引：62

作者：

Schwemmle, M ^{[1
]}

Jehle, C ^{[1
]}

Formella, S ^{[1
]}

Staeheli, P ^{[1
]}

机构：

[1] Univ Freiburg, Dept Virol, D-79104 Freiburg, Germany

来源：

LANCET | 1999年 / 354卷 / 9194期

关键词：

D O I：

10.1016/S0140-6736(99)04703-0

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Human bornavirus RW98, whose genome differs by 3-4% from previous isolates, is almost identical to a rat-adapted laboratory strain. Other human bornaviruses are also strongly related to virus strains frequently used for experiments in the various laboratories reporting human bornavirus, questioning a human origin of isolates known to date.

引用

页码：1973 / 1974

页数：2

共 5 条

[1]

Bauer J, 1997, LANCET, V350, P1002, DOI 10.1016/S0140-6736(05)64066-4

[2] Detection and sequence analysis of borna disease virus p24 RNA from peripheral blood mononuclear cells of patients with mood disorders or schizophrenia and of blood donors [J].