Amifostine in the management of radiation-induced and chemo-induced mucositis

被引:48
作者
Bensadoun, Rene-Jean
Schubert, Mark M.
Lalla, Rajesh V.
Keefe, Dorothy
机构
[1] Ctr Antoine Lacassagne, Dept Radiat Oncol, F-06189 Nice 2, France
[2] Univ Washington, Dept Oral Med, Oral Med Serv, Seattle Canc Care Alliance, Seattle, WA 98109 USA
[3] Univ Connecticut, Ctr Hlth, Dept Oral Hlth & Diagnost Sci MC1605, Farmington, CT 06030 USA
[4] Univ Adelaide, Dept Med, Adelaide, SA 5001, Australia
关键词
amifostine; mucositis; radiotheraphy; chemotheraphy;
D O I
10.1007/s00520-006-0047-4
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Introduction: Mucositis is a significant complication of cancer therapy, with important clinical and economic implications. In June 2005, the Mucositis Study Group of the Multinational Association of Supportive Care in Cancer/International Society for Oral Oncology (MASCC/ISOO) conducted an evidence-based update review of the literature on mucositis. The goal of this literature review is to update previously published guidelines for the management of mucositis. Results: This article reports the findings of the subgroup charged with reviewing the literature related to amifostine.
引用
收藏
页码:566 / 572
页数:7
相关论文
共 43 条
[1]   Effect of amifostine on toxicities associated with radiochemotherapy in patients with locally advanced non-small-cell lung cancer [J].
Antonadou, D ;
Throuvalas, N ;
Petridis, A ;
Bolanos, N ;
Sagriotis, A ;
Synodinou, M .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2003, 57 (02) :402-408
[2]   Radiotherapy or chemotherapy followed by radiotherapy with or without amifostine in locally advanced lung cancer [J].
Antonadou, D .
SEMINARS IN RADIATION ONCOLOGY, 2002, 12 (01) :50-58
[3]   Prophylactic use of amifostine to prevent radiochemotherapy-induced mucositis and xerostomia in head-and-neck cancer [J].
Antonadou, D ;
Pepelassi, M ;
Synodinou, M ;
Puglisi, M ;
Throuvalas, N .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2002, 52 (03) :739-747
[4]   Phase II evaluation of amifostine as an esophageal mucosal protectant in the treatment of limited-stage small cell lung cancer with chemotherapy and twice-daily radiation [J].
Arquette, M ;
Wasserman, T ;
Govindan, R ;
Garfield, D ;
Senzer, N ;
Gillenwater, H ;
Socinski, M .
SEMINARS IN RADIATION ONCOLOGY, 2002, 12 (01) :59-61
[5]   Protective effect of amifostine during fractionated radiotherapy in patients with pelvic carcinomas: Results of a randomized trial [J].
Athanassiou, H ;
Antonadou, D ;
Coliarakis, N ;
Kouveli, A ;
Synodinou, M ;
Paraskevaidis, M ;
Sarris, G ;
Georgakopoulos, GR ;
Panousaki, K ;
Karageorgis, P ;
Throuvalas, N .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2003, 56 (04) :1154-1160
[6]   Preliminary data of the GORTEC 2000-02 phase III trial comparing intravenous and subcutaneous administration of amifostine for head and neck tumors treated by external radiotherapy [J].
Bardet, E ;
Martin, L ;
Calais, G ;
Tuchais, C ;
Bourhis, J ;
Rhein, B ;
Feham, N ;
Alphonsi, M .
SEMINARS IN ONCOLOGY, 2002, 29 (06) :57-60
[7]   Intrarectal application of amifostine for the prevention of radiation-induced rectal injury [J].
Ben-Josef, E ;
Han, S ;
Tobi, M ;
Vargas, BJ ;
Stamos, B ;
Kelly, L ;
Biggar, S ;
Kaplan, I .
SEMINARS IN RADIATION ONCOLOGY, 2002, 12 (01) :81-85
[8]   A pilot study of topical intrarectal application of amifostine for prevention of late radiation rectal injury [J].
Ben-Josef, E ;
Han, S ;
Tobi, M ;
Shaw, LM ;
Bonner, HS ;
Vargas, BJ ;
Prokop, S ;
Stamos, B ;
Kelly, L ;
Biggar, S ;
Kaplan, I .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2002, 53 (05) :1160-1164
[9]   Lack of cytoprotective effect of amifostine following HLA-identical sibling transplantation for advanced myelodysplastic syndrome (MDS): a pilot study [J].
Benesch, M ;
McDonald, GB ;
Schubert, M ;
Appelbaum, FR ;
Deeg, HJ .
BONE MARROW TRANSPLANTATION, 2003, 32 (11) :1071-1075
[10]   New dosing regimens for amifostine: A pilot study to compare the relative bioavailability of oral and subcutaneous administration with intravenous infusion [J].
Bonner, HS ;
Shaw, LM .
JOURNAL OF CLINICAL PHARMACOLOGY, 2002, 42 (02) :166-174