Tuning the sensitivity of a foldamer-based mercury sensor by its folding energy

被引：226

作者：

Zhao, Yan ^{[1
]}

Zhong, Zhenqi ^{[1
]}

机构：

[1] Iowa State Univ, Dept Chem, Ames, IA 50011 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2006年 / 128卷 / 31期

关键词：

D O I：

10.1021/ja062001i

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A fluorescent sensor for Hg2+ was obtained by incorporation of two methionine units into a cholate hexamer and by attaching a Dansyl group at the chain end. Folding could be made highly favorable or unfavorable in different solvents. Because folding was required to bring the sulfur groups together to chelate the mercury ion, binding affinity of the foldamer and, thus, its sensitivity as a sensor, could be tuned over broad ranges (at least 5 orders of magnitude) by solvent changes. Copyright © 2006 American Chemical Society.

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页码：9988 / 9989

页数：2

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