Predictors of effective bilateral subthalamic nucleus stimulation for PD

被引：213

作者：

Charles, PD

Van Blercom, N

Krack, P

Lee, SL

Xie, J

Besson, G

Benabid, AL

Pollak, P

机构：

[1] Univ Grenoble 1, Dept Clin & Biol Neurosci, F-38043 Grenoble 9, France

[2] Vanderbilt Univ, Med Ctr, Nashville, TN USA

来源：

NEUROLOGY | 2002年 / 59卷 / 06期

关键词：

D O I：

10.1212/WNL.59.6.932

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

To identify factors predictive of effective bilateral subthalamic nucleus (STN) stimulation for PD with severe motor complications, pre- and postoperative Unified PD Rating Scale (UPDRS) scores were analyzed in a series of 54 patients who received bilateral STN stimulation. Younger age and levodopa responsiveness predict a favorable response to bilateral STN stimulation. For individual PD symptoms, those that improve with a supra-threshold dose levodopa challenge are likely to improve with stimulation.

引用

页码：932 / 934

页数：3

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