Prevalence of spondyloarthritis in Terceira, Azores:: a population based study

被引:21
作者
Bruges-Armas, J [1 ]
Lima, C
Peixoto, MJ
Santos, P
Mendonça, D
da Silva, BM
Herrero-Beaumont, G
Calin, A
机构
[1] Hosp Santo Espirito, Med Interna Serv, Lab Imunogenet Internal Med & Radiol, P-9700 Angra do Heroismo, Azores, Portugal
[2] Ctr Histocompatibilidade Ctr, Genet Mol Lab, Coimbra, Portugal
[3] Inst Ciencias Biomed, Abel Salazar, Porto, Portugal
[4] Fdn Jimenez Dias, Dept Rheumatol, Madrid, Spain
[5] Royal Natl Hosp Rheumat Dis, Bath BA1 1RL, Avon, England
关键词
D O I
10.1136/ard.61.6.551
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: To determine the prevalence of spondyloarthritis (SpA) in the Caucasian population of Terceira Island, Azores, Methods: Study subjects were recruited from people over the age of 50 years from one half of the island of Terceira (n=24 561). Seventy eight men and 78 women from each five year age group were selected, giving a total of 468 men and 468 women available for study, of whom 490 agreed to take part, These subjects were assessed by dorsal, lumbar, and pelvic radiography. Radiological socroiliitis was identified in eight patients on whom sacroiliac computed tomography scans were performed, HLA class I typing by polymerase chain reaction with sequence-specific primers was carried out in seven cases. Results: SpA was present in eight subjects (1.6%, 95% Cl 0.8 to 2.7%), including seven men (27%) and one woman (0.4%). Three (1.2%) male patients with definite ankylosing spondylitis were HLA-B27 positive. Only one person had a previous diagnosis of SpA. Conclusion: These data complement previous studies in European countries on SpA prevalence and establish an estimate of the overall prevalence of SpA in a southern European population.
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页码:551 / 553
页数:3
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