Hemophagocytic lymphohistiocytosis

被引:13
作者
Filipovich, AH [1 ]
机构
[1] Childrens Hosp, Med Ctr, Div Hematol Oncol, Immunodeficiency & Histiocytosis Program, Cincinnati, OH 45229 USA
关键词
D O I
10.1016/S0889-8561(01)00009-1
中图分类号
R392 [医学免疫学];
学科分类号
100102 [免疫学];
摘要
The current understanding regarding the etiology and pathogenesis of hemophagocytic lymphohistiocytosis (HLH) is described. Diagnostic criteria for clinical and laboratory diagnosis, as well as effective therapies, are reviewed.
引用
收藏
页码:281 / +
页数:21
相关论文
共 55 条
[1]
Allen M, 2001, HAEMATOLOGICA, V86, P499
[2]
Arico M, 1996, LEUKEMIA, V10, P197
[3]
Aricò M, 1999, AM J MED GENET, V87, P329, DOI 10.1002/(SICI)1096-8628(19991203)87:4<329::AID-AJMG9>3.0.CO
[4]
2-M
[5]
Successful correction of hemophagocytic lymphohistiocytosis with related or unrelated bone marrow transplantation [J].
Baker, KS ;
DeLaat, CA ;
Steinbuch, M ;
Gross, TG ;
Shapiro, RS ;
Loechelt, B ;
Harris, R ;
Filipovich, AH .
BLOOD, 1997, 89 (10) :3857-3863
[6]
Defective CTLA-4 cycling pathway in Chediak-Higashi syndrome: A possible mechanism for deregulation of T lymphocyte activation [J].
Barrat, FJ ;
Le Deist, F ;
Benkerrou, M ;
Bousso, P ;
Feldmann, J ;
Fischer, A ;
de Saint Basile, G .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (15) :8645-8650
[7]
Accelerated phase in partial albinism with immunodeficiency (Griscelli syndrome): genetics and stem cell transplantation in a 2-month-old girl [J].
Baumeister, FAM ;
Stachel, D ;
Schuster, F ;
Schmid, I ;
Schaller, M ;
Wolff, H ;
Weiss, M ;
Belohradsky, BH .
EUROPEAN JOURNAL OF PEDIATRICS, 2000, 159 (1-2) :74-78
[8]
Certain S, 2000, BLOOD, V95, P979
[9]
Characteristic immune abnormalities in hemophagocytic lymphohistiocytosis [J].
Egeler, RM ;
Shapiro, R ;
Loechelt, B ;
Filipovich, A .
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 1996, 18 (04) :340-345
[10]
Spectrum of perforin gene mutations in familial hemophagocytic lymphohistiocytosis [J].
Ericson, KG ;
Fadeel, B ;
Nilsson-Ardnor, S ;
Söderhäll, C ;
Samuelsson, A ;
Janka, G ;
Schneider, M ;
Gürgey, A ;
Yalman, N ;
Révész, T ;
Egeler, RM ;
Jahnukainen, K ;
Storm-Mathiesen, I ;
Haraldsson, A ;
Poole, J ;
de Saint Basile, G ;
Nordenskjöld, M ;
Henter, JI .
AMERICAN JOURNAL OF HUMAN GENETICS, 2001, 68 (03) :590-597