Depression in patients with temporal lobe epilepsy is related to mesial temporal sclerosis

被引：178

作者：

Quiske, A ^{[1
]}

Helmstaedter, C ^{[1
]}

Lux, S ^{[1
]}

Elger, CE ^{[1
]}

机构：

[1] Univ Bonn, Hosp Epileptol, D-53105 Bonn, Germany

来源：

EPILEPSY RESEARCH | 2000年 / 39卷 / 02期

关键词：

depression; temporal lobe epilepsy; mesial temporal sclerosis; limbic system;

D O I：

10.1016/S0920-1211(99)00117-5

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Depression is a frequent psychiatric symptom in epilepsy and has been related to epilepsy of temporal origin, especially of left-sided foci. No study differentiated the precise localization of the epileptogenic lesion within the temporal lobe. Regarding this issue, we evaluated depression assessed by the Beck Depression Inventory in 60 patients with temporal lobe epilepsy, with particular consideration of morphological abnormalities within the temporal lobe (mesial temporal sclerosis (MTS) versus neocortical lesions) and lateralization of the lesion. Multivariate analyses indicated significant higher depression scores in MTS independent of the lateralization of the lesion. Depression was a good indicator for MTS but not vice versa. Hence, MTS can be discussed as a predisposing factor for the development of mood disorders in focal epilepsy. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：121 / 125

页数：5

共 26 条

[1] DEPRESSION, ANXIETY, AND TEMPORAL-LOBE EPILEPSY - LATERALITY OF FOCUS AND SYMPTOMS [J].