Synthesis of aromatic and heteroaromatic oligoamides on methoxypoly(ethylene glycol) as solubilizing polymer support

被引：11

作者：

König, B ^{[1
]}

Papke, U ^{[1
]}

Rödel, M ^{[1
]}

机构：

[1] Univ Regensburg, Inst Organ Chem, D-93040 Regensburg, Germany

来源：

NEW JOURNAL OF CHEMISTRY | 2000年 / 24卷 / 01期

关键词：

D O I：

10.1039/a904289j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A protecting-group-free procedure for the synthesis of short carbo- and heteroaromatic oligoamide chains on MeO-PEG as solubilizing support is introduced. Starting from nitrocarboxylic acids, oligoamides of carboxylic acids derived from N-methylpyrrole, N-methylimidazole and aniline are synthesized that contain up to five arene units. The polymer support facilitates work up procedures and markedly improves the otherwise poor solubility of the products. Each coupling step is monitored by H-1-NMR spectroscopy without cleavage of the product from the polymeric support.

引用

页码：39 / 45

页数：7

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