LS-SNP/PDB: annotated non-synonymous SNPs mapped to Protein Data Bank structures

被引：54

作者：

Ryan, Michael ^{[2
]}

Diekhans, Mark ^{[3
]}

Lien, Stephanie ^{[1
]}

Liu, Yun ^{[1
]}

Karchin, Rachel ^{[1
]}

机构：

[1] Johns Hopkins Univ, Dept Biomed Engn, Inst Computat Med, Baltimore, MD 21218 USA

[2] George Mason Univ, Dept Bioinformat, Fairfax, VA 22030 USA

[3] Univ Calif Santa Cruz, Dept Biomol Engn, Santa Cruz, CA 95064 USA

来源：

BIOINFORMATICS | 2009年 / 25卷 / 11期

关键词：

TO-AUTOINTEGRATION FACTOR; ICAM-1; INFORMATION; SYSTEM; GENOME; MAC-1; DNA;

D O I：

10.1093/bioinformatics/btp242

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

LS-SNP/PDB is a new WWW resource for genome-wide annotation of human non-synonymous (amino acid changing) SNPs. It serves high-quality protein graphics rendered with UCSF Chimera molecular visualization software. The system is kept up-to-date by an automated, high-throughput build pipeline that systematically maps human nsSNPs onto Protein Data Bank structures and annotates several biologically relevant features.

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收藏

页码：1431 / 1432

页数：2

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