Transient portal vein thrombosis in liver cirrhosis

被引：51

作者：

Qi, Xingshun ^{[1
]}

Guo, Xiaozhong ^{[1
]}

Yoshida, Eric M. ^{[2
]}

Mendez-Sanchez, Nahum ^{[3
]}

De Stefano, Valerio ^{[4
]}

Tacke, Frank ^{[5
]}

Mancuso, Andrea ^{[6
,7
]}

Sugawara, Yasuhiko ^{[8
]}

Yang, Sien-Sing ^{[9
,10
]}

Teschke, Rolf ^{[11
]}

Arora, Ankur ^{[12
]}

Valla, Dominique-Charles ^{[13
,14
,15
]}

机构：

[1] Gen Hosp Shenyang Mil Area, Dept Gastroenterol, Liver Cirrhosis Study Grp, 83 Wenhua Rd, Shenyang 110840, Liaoning, Peoples R China

[2] Vancouver Gen Hosp, Div Gastroenterol, Vancouver, BC, Canada

[3] Med Clin & Fdn, Liver Res Unit, Mexico City, DF, Mexico

[4] Univ Cattolica Sacro Cuore, Inst Hematol, Rome, Italy

[5] Rhein Westfal TH Aachen, Dept Med III, Aachen, Germany

[6] ARNAS Civico, Dept Internal Med, Palermo, Italy

[7] Osped Niguarda Ca Granda, Hepatol & Gastroenterol, Milan, Italy

[8] Kumamoto Univ, Postgrad Sch Med Sci, Dept Transplantat & Pediat Surg, Kumamoto, Japan

[9] Cathay Gen Hosp, Liver Unit, Taipei, Taiwan

[10] Fu Jen Catholic Univ, Sch Med, Taipei, Taiwan

[11] Klinikum Hanau, Dept Internal Med 2, Div Gastroenterol & Hepatol, D-63450 Hanau, Germany

[12] Worthing Dist Hosp, Western Sussex NHS Fdn Trust, Dept Radiol, Worthing, W Sussex, England

[13] Hop Beaujon, AP HP, Serv Hepatol, Paris, France

[14] Univ Paris Diderot, Paris, France

[15] INSERM, Paris, France

来源：

BMC MEDICINE | 2018年 / 16卷

基金：

中国博士后科学基金;

关键词：

Portal vein thrombosis; Liver cirrhosis; Recanalization; Anticoagulation; Transient; NATURAL COURSE; VENOUS THROMBOSIS; CONTROLLED-TRIAL; ANTICOAGULATION; METAANALYSIS; MANAGEMENT; EFFICACY; OUTCOMES; TRANSPLANTATION; DISEASE;

D O I：

10.1186/s12916-018-1069-8

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In real-world clinical practice, the acceptance of anticoagulation therapy in the management of portal vein thrombosis (PVT) in patients with cirrhosis is limited by the fear of an increased bleeding risk. Additionally, accumulating evidence indicates that spontaneous recanalization of PVT may occur in the absence of antithrombotic treatment. Therefore, risk stratification based on outcomes in such patients is crucial for determining a therapeutic strategy. In this paper, we draw attention to the distinct clinical entity, "transient PVT" by introducing two cases with PVT that spontaneously recanalized in the absence of antithrombotic treatment. We reviewed the available data regarding the probability of and predictors for spontaneous recanalization of PVT. Available data suggest singling out transient thrombosis in the natural history of PVT in patients with cirrhosis because of its prognostic and management implications.

引用

页数：11

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