The use of ondansetron to treat pruritus associated with intrathecal morphine in two paediatric patients

被引：12

作者：

Arai, L ^{[1
]}

Stayer, S ^{[1
]}

Schwartz, R ^{[1
]}

Dorsey, A ^{[1
]}

机构：

[1] ST CHRISTOPHERS HOSP CHILDREN, DEPT ANESTHESIA & CRIT CARE, PHILADELPHIA, PA 19134 USA

来源：

PAEDIATRIC ANAESTHESIA | 1996年 / 6卷 / 04期

关键词：

intrathecal morphine; ondansetron; pruritus;

D O I：

10.1111/j.1460-9592.1996.tb00460.x

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Intrathecal morphine is an effective technique for providing postoperative analgesia after major surgical procedures in children. Pruritus is a common side effect associated with intrathecal morphine. We report two patients who experienced significant pruritus associated with intrathecal morphine administration and were successfully treated with ondansetron Ondansetron appears to be a beneficial and safe method of relieving pruritus associated with intrathecal morphine.

引用

页码：337 / 339

页数：3

共 16 条

[1]

[Anonymous], 1990, ANN NY ACAD SCI

[2] SUBHYPNOTIC DOSES OF PROPOFOL RELIEVE PRURITUS INDUCED BY EPIDURAL AND INTRATHECAL MORPHINE [J].

BORGEAT, A ;

WILDERSMITH, OHG ;

SAIAH, M ;

RIFAT, K .

ANESTHESIOLOGY, 1992, 76 (04) :510-512

[3] EFFICACY OF ONDANSETRON (GR-38032F) AND THE ROLE OF SEROTONIN IN CISPLATIN-INDUCED NAUSEA AND VOMITING [J].

CUBEDDU, LX ;

HOFFMANN, IS ;

FUENMAYOR, NT ;

FINN, AL .

NEW ENGLAND JOURNAL OF MEDICINE, 1990, 322 (12) :810-816

[4]

HORTA ML, 1993, REGION ANESTH, V18, P118

[5]

JONES SEF, 1984, BRIT J ANAESTH, V86, P571

[6]

Juneja M M, 1991, J Ky Med Assoc, V89, P319

[7] COMPARISON OF ONDANSETRON VERSUS PLACEBO TO PREVENT POSTOPERATIVE NAUSEA AND VOMITING IN WOMEN UNDERGOING AMBULATORY GYNECOLOGIC SURGERY [J].

MCKENZIE, R ;

KOVAC, A ;

OCONNOR, T ;

DUNCALF, D ;

ANGEL, J ;

GRATZ, I ;

TOLPIN, E ;

MCLESKEY, C ;

JOSLYN, A .

ANESTHESIOLOGY, 1993, 78 (01) :21-28

[8]

MORGAN PJ, 1991, REGION ANESTH, V16, P84

[9] REVERSAL OF EPIDURAL MORPHINE-INDUCED RESPIRATORY DEPRESSION AND PRURITUS WITH NALBUPHINE [J].

PENNING, JP ;

SAMSON, B ;

BAXTER, AD .

CANADIAN JOURNAL OF ANAESTHESIA-JOURNAL CANADIEN D ANESTHESIE, 1988, 35 (06) :599-604

[10] ONDANSETRON FOR PRURITUS DUE TO CHOLESTASIS [J].

RADERER, M ;

MULLER, C ;

SCHEITHAUER, W .

NEW ENGLAND JOURNAL OF MEDICINE, 1994, 330 (21) :1540-1540

← 1 2 →