Self-organization of spheroidal molecular assemblies in polar solvents

被引：38

作者：

Grawe, T

Schrader, T

Gurrath, M

Kraft, A

Osterod, F

机构：

[1] Univ Dusseldorf, Inst Organ Chem & Makromol Chem, D-40225 Dusseldorf, Germany

[2] Univ Dusseldorf, Inst Pharmazeut Chem, D-40225 Dusseldorf, Germany

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 01期

关键词：

D O I：

10.1021/ol9910924

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] We report a number of 1:1 noncovalent complexes composed of a symmetrical trisphosphonate and various symmetrical trisammonium or trisamidinium compounds. The spheroidal complexes show high thermodynamic stability, with association constants K-a reaching 10(6) M-1 in methanol and in some cases even exceeding 10(3) M-1 in water. The observed K-a values correlate well with the different degree of preorganization of the complexation partners.

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页码：29 / 32

页数：4

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