Effects of PhD examination stress on allopregnanolone and cortisol plasma levels and peripheral benzodiazepine receptor density

被引：79

作者：

Fortuyn, HAD

van Broekhoven, F

Span, PN

Bäckström, T

Zitman, FG

Verkes, RJ

机构：

[1] Univ Nijmegen, Med Ctr, Unit Clin Psychopharmacol & Neuropsychiat, Dept Psychiat 331, NL-6500 HB Nijmegen, Netherlands

[2] Univ Nijmegen, Med Ctr, Dept Chem Endocrinol, Nijmegen, Netherlands

[3] Umea Univ Hosp, Dept Clin Sci Obstet & Gynecol, Umea Neurosteroid Res Ctr, S-90185 Umea, Sweden

来源：

PSYCHONEUROENDOCRINOLOGY | 2004年 / 29卷 / 10期

关键词：

allopregnanolone; peripheral benzodiazepine receptor; cortisol; acute stress; neurosteroids; PhD examination;

D O I：

10.1016/j.psyneuen.2004.02.003

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Peripheral benzodiazepine receptor (PBR) density in blood platelets and plasma allopregnanolone concentration in humans were determined following acute stress as represented by PhD examination. Fifteen healthy PhD students participated. Heart rate, blood pressure, plasma allopregnanolone, plasma cortisol, and PBR density were measured at different time points. Allopregnanolone and cortisol concentration and PBR density were significantly increased during examination. A positive correlation between allopregnanolone and PBR density was found. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：1341 / 1344

页数：4

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