Promises and pitfalls in the reconstitution of immunity in patients who have HIV-1 infection

被引：12

作者：

Gandhi, RT ^{[1
]}

Walker, BD

机构：

[1] Massachusetts Gen Hosp, Partners AIDS Res Ctr, Boston, MA 02114 USA

[2] Massachusetts Gen Hosp, Div Infect Dis, Boston, MA 02114 USA

[3] Harvard Univ, Sch Med, Div AIDS, Boston, MA 02114 USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 2002年 / 14卷 / 04期

关键词：

D O I：

10.1016/S0952-7915(02)00359-X

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Recent studies suggest that immunologic containment of HIV-1 is possible and the immune correlates of this control are being defined. There have been significant advances in our ability to elicit virus-specific immune responses, which have led to viral control in animal models. Although viral escape from the immune system is an important challenge, new strategies for therapeutic and preventative HIV-1 vaccination are being vigorously pursued in human trials.

引用

页码：487 / 494

页数：8

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