Notch signaling in T cell development

被引：110

作者：

Deftos, ML ^{[1
]}

Bevan, MJ ^{[1
]}

机构：

[1] Univ Washington, Howard Hughes Med Inst, Dept Immunol, Seattle, WA 98195 USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 2000年 / 12卷 / 02期

关键词：

D O I：

10.1016/S0952-7915(99)00067-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Notch signaling regulates cell fate decisions during development. Recent experiments suggest that Notch signaling is essential for initial commitment to the T cell lineage and may function together with signals from the pre-TCR and the TCR to regulate subsequent steps of T cell development.

引用

页码：166 / 172

页数：7

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