Expression patterns of two new members of the Semaphorin family in Drosophila suggest early functions during embryogenesis

被引：28

作者：

Khare, N

Fascetti, N

DaRocha, S

Chiquet-Ehrismann, R

Baumgartner, S

机构：

[1] Univ Lund, Dept Cell & Mol Biol, S-22100 Lund, Sweden

[2] Friedrich Miescher Inst, CH-4002 Basel, Switzerland

来源：

MECHANISMS OF DEVELOPMENT | 2000年 / 91卷 / 1-2期

关键词：

Drosophila; Semaphorin; embryogenesis; evolution;

D O I：

10.1016/S0925-4773(99)00297-X

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We report the sequence and expression analysis of two new Drosophila members of the Semaphorin family. Both proteins show the presence of Semaphorin domains and transmembrane domains. Both genes are expressed maternally and in embryos, and reveal distinct expression patterns much earlier than the onset of neurogenesis. We also present an overview of the domain structure of all so far known semaphorins in Drosophila. Furthermore. we compared all Drosophila and C. elegans Semaphorins and discuss them in the light of their evolution. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：393 / 397

页数：5

共 18 条

[1] A novel class of murine semaphorins with homology to thrombospondin is differentially expressed during early embryogenesis [J].