Phytochemical and pharmacological studies on Chinese Paeonia species

被引:69
作者
Ding, HY
Lin, HC [1 ]
Teng, CM
Wu, YC
机构
[1] Kaohsiung Med Univ, Grad Inst Pharmaceut Sci, Kaohsiung 807, Taiwan
[2] Natl Def Med Ctr, Sch Pharm, Taipei 114, Taiwan
[3] Natl Taiwan Univ, Coll Med, Inst Pharmacol, Taipei 100, Taiwan
关键词
Paeonia suffruticosa; Paeonia lactiflora; aromatic acids; monoterpene glycosides; gallotannins; pharmacological activities;
D O I
10.1002/jccs.200000051
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A new monoterpene glycoside, mudanpioside J (3), was isolated from the root cortex of Paeonia suffruticosa. Its structure has been established on the basis of spectral evidence. In addition, six known compounds, campesterol(4), 4-hydroxyacetopenone (5), kaempferol (6), 3-hydroxy-4-methoxybenzoic acid (7), hederagenin (8) and galloylpaeoniflorin (9) were also isolated. A screening test of monoterpene glycosides and aromatic acids derived from P. suffruticosa and P. lactiflora on arachidonic acid, thrombin, collagen and PAF induced rabbit platelet aggregation suggests aromatic acids may play an important role in inhibition of platelet aggregation,inflammation and hemorrhage due to bacterial infection.
引用
收藏
页码:381 / 388
页数:8
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