Nose blowing propels nasal fluid into the paranasal sinuses

被引:103
作者
Gwaltney, JM [1 ]
Hendley, JO
Phillips, CD
Bass, CR
Mygind, N
Winther, B
机构
[1] Univ Virginia, Hlth Sci Ctr, Dept Internal Med, Charlottesville, VA 22908 USA
[2] Univ Virginia, Hlth Sci Ctr, Dept Pediat, Charlottesville, VA 22908 USA
[3] Univ Virginia, Hlth Sci Ctr, Dept Radiol, Charlottesville, VA 22908 USA
[4] Univ Virginia, Hlth Sci Ctr, Dept Otolaryngol Head & Neck Surg, Charlottesville, VA 22908 USA
[5] Univ Virginia, Sch Engn, Dept Mech Engn, Charlottesville, VA USA
[6] Aarhus Univ Hosp, Dept Resp Dis, Aarhus, Denmark
关键词
D O I
10.1086/313661
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Intranasal pressures were measured in adults during nose blowing, sneezing, and coughing and were used for fluid dynamic modeling. Sinus CT scans were performed after instillation of radiopaque contrast medium into the nasopharynx followed by nose blowing, sneezing, and coughing. The mean (+/- SD) maximal intranasal pressure was 66 (+/- 14) mm Hg during 35 nose blows, 4.6 (+/- 3.8) mm Hg during 13 sneezes, and 6.6 (+/- 3.8) mm Hg during 18 coughing bouts. A single nose blow can propel up to 1 mL of viscous fluid in the middle meatus into the maxillary sinus. Sneezing and coughing do not generate sufficient pressure to propel viscous fluid into the sinus. Contrast medium from the nasopharynx appeared in greater than or equal to 1 sinuses in 4 of 4 subjects after a nose blow but not after sneezing or coughing.
引用
收藏
页码:387 / 391
页数:5
相关论文
共 16 条
[1]  
BERG O, 1986, Rhinology (Utrecht), V24, P223
[2]  
DINGLE JH, 1964, ILLNESS HOME STUDY 2, P347
[3]   A DOUBLE-BLIND, PLACEBO-CONTROLLED CLINICAL-TRIAL OF THE EFFECT OF CHLORPHENIRAMINE ON THE RESPONSE OF THE NASAL AIRWAY, MIDDLE-EAR AND EUSTACHIAN-TUBE TO PROVOCATIVE RHINOVIRUS CHALLENGE [J].
DOYLE, WJ ;
MCBRIDE, TP ;
SKONER, DP ;
MADDERN, BR ;
GWALTNEY, JM ;
UHRIN, M .
PEDIATRIC INFECTIOUS DISEASE JOURNAL, 1988, 7 (03) :229-238
[4]  
GIROD S, 1992, EUR RESPIR J, V5, P477
[5]   Randomized controlled trial of clemastine fumarate for treatment of experimental rhinovirus colds [J].
Gwaltney, JM ;
Park, J ;
Paul, RA ;
Edelman, DA ;
OConnor, RR ;
Turner, RB .
CLINICAL INFECTIOUS DISEASES, 1996, 22 (04) :656-662
[6]   Acute community-acquired sinusitis [J].
Gwaltney, JM .
CLINICAL INFECTIOUS DISEASES, 1996, 23 (06) :1209-1225
[7]   COMPUTED TOMOGRAPHIC STUDY OF THE COMMON COLD [J].
GWALTNEY, JM ;
PHILLIPS, CD ;
MILLER, RD ;
RIKER, DK .
NEW ENGLAND JOURNAL OF MEDICINE, 1994, 330 (01) :25-30
[8]   Efficacy of brompheniramine maleate for the treatment of rhinovirus colds [J].
Gwaltney, JM ;
Druce, HM .
CLINICAL INFECTIOUS DISEASES, 1997, 25 (05) :1188-1194
[9]  
HANRATTY TJ, 1983, WAVES FLUID INTERFAC
[10]   RHEOLOGIC PROPERTIES OF NASAL MUCUS FROM PATIENTS WITH CHRONIC SINUSITIS [J].
MAJIMA, Y ;
SAKAKURA, Y ;
HATTORI, M ;
HIRATA, K .
AMERICAN JOURNAL OF RHINOLOGY, 1993, 7 (05) :217-221