The diagnostic accuracy of 18F-Fluorodeoxyglucose PET/CT in patients with gynecological malignancies

被引:55
作者
Grisaru, D
Almog, B
Levine, C
Metser, U
Fishman, A
Lerman, H
Lessing, JB
Even-Sapir, E
机构
[1] Tel Aviv Sourasky Med Ctr, Dept Obstet & Gynecol, IL-64239 Tel Aviv, Israel
[2] Tel Aviv Sourasky Med Ctr, Dept Radiol, IL-64239 Tel Aviv, Israel
[3] Tel Aviv Sourasky Med Ctr, Dept Nucl Med, IL-64239 Tel Aviv, Israel
[4] Tel Aviv Univ, Sackler Fac Med, Meir Med Ctr, Dept Obstet & Gynecol, IL-69978 Tel Aviv, Israel
关键词
positron emission tomography/computerized tomography; staging; follow-up;
D O I
10.1016/j.ygyno.2004.05.053
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Objective. To evaluate the diagnostic accuracy of integrated positron emission tomography/computerized tomography (PET/CT) in patients with gynecological cancer. Methods. Fifty-three consecutive patients with gynecologic malignancies were included. The patients were referred to our tertiary center to undergo a PET/CT scan. The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of PET/CT were compared with the conventional imaging assessments [CT, magnetic resonance imaging (MRI) and ultrasonography (US)]. Results. All tested values were higher for PET/CT than those for the conventional modalities: sensitivity 0.97 vs. 0.40, specificity 0.94 vs. 0.65, PPV 0.97 vs. 0.70, and NPV 0.94 vs. 0.34, respectively. Conclusion. PET/CT is a reliable modality for assessing the extent of disease in patients with gynecologic malignancy. (C) 2004 Elsevier Inc. All rights reserved.
引用
收藏
页码:680 / 684
页数:5
相关论文
共 20 条
[1]   PET imaging in oncology [J].
Bar-Shalom, R ;
Valdivia, AY ;
Blaufox, MD .
SEMINARS IN NUCLEAR MEDICINE, 2000, 30 (03) :150-185
[2]   Contribution of whole-body 18FDG PET imaging in the management of cervical cancer [J].
Belhocine, T ;
Thille, A ;
Fridman, V ;
Albert, A ;
Seidel, L ;
Nickers, P ;
Kridelka, F ;
Rigo, P .
GYNECOLOGIC ONCOLOGY, 2002, 87 (01) :90-97
[3]   Usefulness of 18F-FDG PET in the post-therapy surveillance of endometrial carcinoma [J].
Belhocine, T ;
De Barsy, C ;
Hustinx, R ;
Willems-Foidart, J .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2002, 29 (09) :1132-1139
[4]   Peritoneal metastases: Detection with spiral CT in patients with ovarian cancer [J].
Coakley, FV ;
Choi, PH ;
Gougoutas, CA ;
Pothuri, B ;
Venkatraman, E ;
Chi, D ;
Bergman, A ;
Hricak, H .
RADIOLOGY, 2002, 223 (02) :495-499
[5]   Positron emission and computed X-ray tomography: a coming together [J].
Costa, DC ;
Visvikis, D ;
Crosdale, I ;
Pigden, I ;
Townsend, C ;
Bomanji, J ;
Prvulovich, E ;
Lonn, A ;
Ell, PJ .
NUCLEAR MEDICINE COMMUNICATIONS, 2003, 24 (04) :351-358
[6]  
De Rosa V., 1995, European Journal of Gynaecological Oncology, V16, P123
[7]   PET/CT: a new road map [J].
Ell, PJ ;
von Schulthess, GK .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2002, 29 (06) :719-720
[8]   Posttherapy surveillance monitoring of cervical cancer by FDG-pet [J].
Grigsby, PW ;
Siegel, BA ;
Dehdashti, F ;
Mutch, DG .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2003, 55 (04) :907-913
[9]   Lymph node staging by positron emission tomography in patients with carcinoma of the cervix [J].
Grigsby, PW ;
Siegel, BA ;
Dehdashti, F .
JOURNAL OF CLINICAL ONCOLOGY, 2001, 19 (17) :3745-3749
[10]   Body CT and oncologic imaging [J].
Hopper, KD ;
Singapuri, K ;
Finkel, A .
RADIOLOGY, 2000, 215 (01) :27-40