Panencephalopathic type of Creutzfeldt-Jakob disease associated with cadaveric dura mater graft

被引：27

作者：

Yamada, M

Itoh, Y

Suematsu, N

Matsushita, M

Otomo, E

机构：

[1] YOKUFUKAI GERIATR HOSP,DEPT INTERNAL MED,SUGINAMI KU,TOKYO 168,JAPAN

[2] YOKUFUKAI GERIATR HOSP,DEPT PATHOL,SUGINAMI KU,TOKYO 168,JAPAN

[3] UNIV TOKYO,DEPT PSYCHIAT,BUNKYO KU,TOKYO 113,JAPAN

来源：

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 1997年 / 63卷 / 04期

关键词：

Creutzfeldt-Jakob disease; cadaveric dura matter graft; prion protein;

D O I：

10.1136/jnnp.63.4.524

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A 52 year old man with Creutzfeldt-Jakob disease who received a cadaveric dura mater graft 99 months before the onset is reported. The prion protein gene was homozygous for methionine at the polymorphic codon 129. Neuropathological examination disclosed a panencephalopathic type of Creutzfeldt-Jakob disease which was characterised by severe involvement of the cerebral white matter and cerebellum, as well as of the cerebral cortical and deep grey matter. Thus the panencephalopathic type of Creutzfeldt-Jakob disease may occur in association with cadaveric dura mater grafts.

引用

页码：524 / 527

页数：4

共 13 条

[1]

BELL JE, 1996, PRION DIS, P59

[2]

BROWN P, 1996, PRION DIS, P139

[3] CREUTZFELDT-JAKOB-DISEASE AND LYOPHILIZED DURA-MATER GRAFTS - REPORT OF 2 CASES [J].