Diterpenoids from the roots of Salvia bracteata

From the roots of Salvia bracteata Banks and Sol. in Russell, Aleppo. two new diterpenoids Salvibracteone (1) and bractealine (2) have been isolated together with eight known diterpenoids. The structures of the new compounds were established by spectroscopic analysis. The diterpenoids and the crude extract were tested against standard bacterial strains. The crude extract, the new compound bractealine (1), and the known compound horminone showed activity against B. subtilis, S. aureus, and S. epidermidis. Ferruginol had slight activity against these strains. (C) 1999 Elsevier Science Ltd. All rights reserved.