Methotrexate effects in patients with rheumatoid arthritis with cardiovascular comorbidity

被引：135

作者：

Landewé, RBM

van den Borne, BEEM

Breedveld, FC

Dijkmans, BAC

机构：

[1] Univ Hosp Maastricht, Dept Rheumatol, NL-6202 AZ Maastricht, Netherlands

[2] Catharina Hosp, Dept Pulmonol, Eindhoven, Netherlands

[3] Leiden Univ, Med Ctr, NL-2300 RA Leiden, Netherlands

[4] Free Univ Amsterdam Hosp, Amsterdam, Netherlands

来源：

LANCET | 2000年 / 355卷 / 9215期

关键词：

D O I：

10.1016/S0140-6736(00)02222-4

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

Methotrexate, an antirheumatic drug that may increase serum homocysteine, significantly increases mortality in patients with rheumatoid arthritis and cardiovascular comorbidity.

引用

页码：1616 / 1617

页数：2

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[3]

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[4]

van den Borne BEEM, 1998, ARTHRITIS RHEUM-US, V41, P1930

[5]

WOLFE F, 1998, ARTHRITIS RHEUM S, V9, P188

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