Total synthesis of 1,3-dideoxynojirimycin

被引：13

作者：

Gryko, D

Jurczak, J

机构：

[1] POLISH ACAD SCI,INST ORGAN CHEM,PL-01224 WARSAW,POLAND

[2] WARSAW UNIV,DEPT CHEM,PL-02093 WARSAW,POLAND

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 47期

关键词：

D O I：

10.1016/S0040-4039(97)10166-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Addition of allyl bromide (5) to N-benzyl-N-carbobenzoxy-O-tert-butyldimethyl-D-serinal (4) afforded with high diastereoselectivity anti-adduct 6 which subsequently transformed into(2R,4S,5R)-1,3-dideoxynojirimycin (1). (C) 1997 Elsevier Science Ltd.

引用

页码：8275 / 8278

页数：4

共 22 条

[11] RATIONAL DESIGN OF AZA SUGARS VIA BIOCATALYSIS - MANNOJIRIMYCIN AND OTHER GLYCOSIDASE INHIBITORS [J].