Modular iminopyridine ligands.: Application to the enantioselective copper(II)-catalyzed Henry reaction

被引：82

作者：

Blay, Gonzalo ^{[1
]}

Climent, Estela ^{[1
]}

Fernandez, Isabel ^{[1
]}

Hernandez-Olmos, Victor ^{[1
]}

Pedro, Jose R. ^{[1
]}

机构：

[1] Univ Valencia, Fac Quim, Dept Quim Organ, E-46100 Burjassot, Valencia, Spain

来源：

TETRAHEDRON-ASYMMETRY | 2006年 / 17卷 / 14期

关键词：

D O I：

10.1016/j.tetasy.2006.07.025

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Chiral iminopyridines prepared in a modular fashion from monoterpenic (camphor-derived) ketones and pyridinylalkylamines catalyze the enantioselective Henry (nitro aldol) reaction between nitromethane and o-anisol in the presence of copper(II) acetate, with high yields and good ee (up to 86%) under straightforward experimental conditions without the need for air or moisture exclusion. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：2046 / 2049

页数：4

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