Novel non-nucleoside inhibitors of human immunodeficiency virus type 1 reverse transcriptase .6. 2-indol-3-yl- and 2-azaindol-3-yl-dipyridodiazepinones

被引：61

作者：

Kelly, TA

McNeil, DW

Rose, JM

David, E

Shih, CK

Grob, PM

机构：

[1] Research and Development Center, Boehringer Ingelheim Pharm. Inc., 900 Ridgebury Road, Ridgefield

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1997年 / 40卷 / 15期

关键词：

D O I：

10.1021/jm960837y

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Modification of the non-nucleoside inhibitor of HIV-1 reverse transcriptase nevirapine (Viramune) by incorporation of a 2-indolyl substituent confers activity against several mutant forms of the enzyme.

引用

页码：2430 / 2433

页数：4

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