Molecular and immunological analyses of the Borrelia turicatae Bdr protein family

被引：13

作者：

Carlyon, JA

Roberts, DM

Theisen, M

Sadler, C

Marconi, RT ^{[1
]}

机构：

[1] Virginia Commonwealth Univ, Med Coll Virginia, Dept Microbiol & Immunol, Richmond, VA 23298 USA

[2] Mary Baldwin Coll, Dept Biol, Staunton, VA 24401 USA

[3] Statens Serum Inst, DK-2300 Copenhagen, Denmark

来源：

INFECTION AND IMMUNITY | 2000年 / 68卷 / 04期

关键词：

D O I：

10.1128/IAI.68.4.2369-2373.2000

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Here, we describe the molecular and immunological characterization of the bdr gene family of Borrelia turicatae, a relapsing-fever spirochete. Nine bdr alleles belonging to two different subfamilies were sequenced and localized to linear plasmids. Anti-Bdr antiserum was generated and used to analyze Bdr expression in pre- and postinfection isogenic populations. The analyses presented here provide a detailed characterization of the Bdr proteins in a relapsing-fever spirochete species, enhancing our understanding of these proteins at the genus-wide level.

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收藏

页码：2369 / 2373

页数：5

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