(De)constructing mitochondria: What for?

被引：126

作者：

Dimmer, Kai S.

Scorrano, Luca

机构：

[1] Dulbecco-Telethon Institute, Venetian Institute of Molecular Medicine

来源：

PHYSIOLOGY | 2006年 / 21卷

关键词：

D O I：

10.1152/physiol.00010.2006

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Mitochondria are dynamic organelles, essential for cell life and death. The morphoplogy of this organelle is determined by fission, controlled by a growing set of "mitochondria shaping" proteins, which influence crucial signally cascades including apoptosis.

引用

收藏

页码：233 / 241

页数：9

相关论文

共 122 条

[1] OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28 [J].

Alexander, C ;

Votruba, M ;

Pesch, UEA ;

Thiselton, DL ;

Mayer, S ;

Moore, A ;

Rodriguez, M ;

Kellner, U ;

Leo-Kottler, B ;

Auburger, G ;

Bhattacharya, SS ;

Wissinger, B .

NATURE GENETICS, 2000, 26 (02) :211-215

[2] Role of essential genes in mitochondrial morphogenesis in Saccharomyces cerevisiae [J].

Altmann, K ;

Westermann, B .

MOLECULAR BIOLOGY OF THE CELL, 2005, 16 (11) :5410-5417

[3] Rab32 is an A-kinase anchoring protein and participates in mitochondrial dynamics [J].

Alto, NM ;

Soderling, J ;

Scott, JD .

JOURNAL OF CELL BIOLOGY, 2002, 158 (04) :659-668

[4] OPA1 R445H mutation in optic atrophy associated with sensorineural deafness [J].

Amati-Bonneau, P ;

Guichet, A ;

Olichon, A ;

Chevrollier, A ;

Viala, F ;

Miot, S ;

Ayuso, C ;

Odent, S ;

Arrouet, C ;

Verny, C ;

Calmels, MN ;

Simard, G ;

Belenguer, P ;

Wang, J ;

Puel, JL ;

Hamel, C ;

Malthièry, Y ;

Bonneau, D ;

Lenaers, G ;

Reynier, P .

ANNALS OF NEUROLOGY, 2005, 58 (06) :958-963

[5] COUPLING MEMBRANES AS ENERGY-TRANSMITTING CABLES .1. FILAMENTOUS MITOCHONDRIA IN FIBROBLASTS AND MITOCHONDRIAL CLUSTERS IN CARDIOMYOCYTES [J].

AMCHENKOVA, AA ;

BAKEEVA, LE ;

CHENTSOV, YS ;

SKULACHEV, VP ;

ZOROV, DB .

JOURNAL OF CELL BIOLOGY, 1988, 107 (02) :481-495

[6]

[Anonymous], 1995, MOL BIOL CELL

[7] Expression of Mfn2, the Charcot-Marie-Tooth neuropathy type 2A gene, in human skeletal muscle -: Effects of type 2 diabetes, obesity, weight loss, and the regulatory role of tumor necrosis factor α, and interleukin-6 [J].

Bach, D ;

Naon, D ;

Pich, S ;

Soriano, FX ;

Vega, N ;

Rieusset, J ;

Laville, M ;

Guillet, C ;

Boirie, Y ;

Wallberg-Henriksson, H ;

Manco, M ;

Calvani, M ;

Castagneto, M ;

Palacín, M ;

Mingrone, G ;

Zierath, JR ;

Vidal, H ;

Zorzano, A .

DIABETES, 2005, 54 (09) :2685-2693

[8] Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism -: A novel regulatory mechanism altered in obesity [J].

Bach, D ;

Pich, S ;

Soriano, FX ;

Vega, N ;

Baumgartner, B ;

Oriola, J ;

Daugaard, JR ;

Lloberas, J ;

Camps, M ;

Zierath, JR ;

Rabasa-Lhoret, R ;

Wallberg-Henriksson, H ;

Laville, M ;

Palacín, M ;

Vidal, H ;

Rivera, F ;

Brand, M ;

Zorzano, A .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (19) :17190-17197

[9] DYNAMICS OF MITOCHONDRIA IN LIVING CELLS - SHAPE CHANGES, DISLOCATIONS, FUSION, AND FISSION OF MITOCHONDRIA [J].

BEREITERHAHN, J ;

VOTH, M .

MICROSCOPY RESEARCH AND TECHNIQUE, 1994, 27 (03) :198-219

[10] Mdm12p, a component required for mitochondrial inheritance that is conserved between budding and fission yeast [J].

Berger, KH ;

Sogo, LF ;

Yaffe, MP .

JOURNAL OF CELL BIOLOGY, 1997, 136 (03) :545-553

← 1 2 3 4 5 6 7 8 9 10 →