The comparative in vitro activity of clinafloxacin and other antimicrobials against vancomycin-susceptible and vancomycin-resistant enterococci

被引：6

作者：

Itokazu, GS

Nathan, C

Hariharan, R

Kostman, JR

Kabins, SA

Weinstein, RA

机构：

[1] MICHAEL REESE HOSP & MED CTR,DEPT PHARM,CHICAGO,IL 60616

[2] MICHAEL REESE HOSP & MED CTR,DEPT MED,CHICAGO,IL 60616

[3] UNIV ILLINOIS,CHICAGO,IL

[4] MT SINAI HOSP,DEPT MED,CHICAGO,IL

[5] UNIV MED & DENT NEW JERSEY,COOPER HOSP,ROBERT WOOD JOHNSON MED SCH,DIV INFECT DIS,CAMDEN,NJ 08103

来源：

CHEMOTHERAPY | 1996年 / 42卷 / 04期

关键词：

clinvafloxain; in vitro activity; enterococci; vancomycin-resistant; vancomycin-susceptible;

D O I：

10.1159/000239449

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The susceptibilities of 50 unique vancomycin-susceptible (n = 15) and vancomycin-resistant (n = 35) enterococci to 6 antimicrobials were compared, Teicoplanin was consistently the most active agent for all strains, Ampicillin and imipenem were active primarily for vancomycin-sensitive Enterococcus faecalis. Clinafloxacin and ciprofloxacin showed poorer activity compared to prior studies, suggesting that the emergence of quinolone resistance is now occurring in enterococci.

引用

页码：235 / 239

页数：5

共 18 条

[11] COMPARATIVE INVITRO ACTIVITY OF PD-127391, A NEW FLUOROQUINOLONE AGENT, AGAINST SUSCEPTIBLE AND RESISTANT CLINICAL ISOLATES OF GRAM-POSITIVE COCCI [J].