Plasma interleukin-beta and tumor necrosis factor concentrations in obsessive-compulsive disorders

被引：55

作者：

Brambilla, F ^{[1
]}

Perna, G ^{[1
]}

Bellodi, L ^{[1
]}

Arancio, C ^{[1
]}

Bertani, A ^{[1
]}

Perini, G ^{[1
]}

Carraro, C ^{[1
]}

Gava, F ^{[1
]}

机构：

[1] UNIV PADUA, CLIN PSICHIAT, PADUA, ITALY

来源：

BIOLOGICAL PSYCHIATRY | 1997年 / 42卷 / 11期

关键词：

interleukin-beta; tumor necrosis factor-alpha; obsessive-compulsive disorders;

D O I：

10.1016/S0006-3223(96)00495-7

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Plasma interleukin-1 beta (Il-1 beta) and tumor necrosis factor-alpha (TNF-alpha) concentrations, were measured twice, at a 48-hour interval, in 27 drug-free obsessive-compulsive patients (12 women and 15 men) and in 27 sex-age-matched healthy controls. Il-1 beta and TNF-alpha concentrations were significantly lower in patients than in controls, whereas there were no differences in either group between men and women, between the samples of the two days, or, in the patients, between those who had and those who had not been previously treated with psychopharmacologic drugs. (C) 1997 Society of Biological Psychiatry.

引用

页码：976 / 981

页数：6

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