Three-component coupling of alkynes, Baylis-Hillman adducts and sodium azide: a new synthesis of substituted triazoles

被引：34

作者：

Chandrasekhar, S ^{[1
]}

Basu, D ^{[1
]}

Rambabu, C ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Div Organ Chem, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 18期

关键词：

multi-component coupling; click synthesis; triazoles; Baylis-Hillman adduct; terminal alkynes;

D O I：

10.1016/j.tetlet.2006.03.037

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A three-component coupling was used to prepare a series of 1,4-disubstituted-1,2,3-triazoles from the corresponding acetylated Baylis-Hillman adducts, sodium azide and terminal alkynes. This one-pot reaction further increases the efficacy of 'Click' synthesis and diversifies the preparation of multi-functional 1,4-disubstituted-1,2,3-triazoles. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：3059 / 3063

页数：5

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