Correlation between the elastase activity index and invasiveness of clinical isolates of Aspergillus fumigatus

被引：53

作者：

Blanco, JL

Hontecillas, R

Bouza, E ^{[1
]}

Blanco, I

Pelaez, T

Muñoz, P

Molina, JP

Garcia, ME

机构：

[1] Hosp Gen Univ Gregorio Maranon, Serv Microbiol Clin & Enfermedades Infecciosas, Madrid 28007, Spain

[2] Univ Complutense Madrid, Fac Vet, Dept Patol Anim 1, Madrid, Spain

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2002年 / 40卷 / 05期

关键词：

D O I：

10.1128/JCM.40.5.1811-1813.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We calculated an elastase activity index (EAI) by dividing the diameter of the elastin lysis halo by the fungal growth diameter. After 10 days' incubation at 37degreesC, all strains but one obtained from invasive aspergillosis showed an EAI greater than or equal to 1. Of the 18 strains obtained from colonized patients, only 4 (22.2%) had an EAI greater than or equal to 1, whereas neither of the strains isolated from patients with fungus ball reached this value. Overall, 44 out of the 142 strains obtained from the environment had an EAI greater than or equal to 1 (30.9%).

引用

页码：1811 / 1813

页数：3

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