cDNA cloning of eel (Anguilla anguilla) somatolactin

被引：23

作者：

May, D ^{[1
]}

Todd, CM ^{[1
]}

RandWeaver, M ^{[1
]}

机构：

[1] BRUNEL UNIV,DEPT BIOL & BIOCHEM,UXBRIDGE UB8 3PH,MIDDX,ENGLAND

来源：

GENE | 1997年 / 188卷 / 01期

关键词：

pituitary; fish; growth hormone prolactin family; nucleotide sequencing; amino acid sequence homology; GROWTH-HORMONE; PITUITARY PROTEIN; RAINBOW-TROUT; PLASMA-LEVELS; COHO SALMON; PROLACTIN; SEQUENCE; STRESS; FISH;

D O I：

10.1016/S0378-1119(96)00777-9

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The nucleotide sequence of the cDNA coding for eel somatolactin (SL), a pituitary hormone belonging to the growth hormone (GH)/prolactin (PRL) family, has been determined. The full-length eel SL cDNA (1213 bp) encodes a protein of 229 amino acids (aa), with a putative signal peptide of 24 aa and a mature protein of 204 aa. Eel SL contains seven Cys residues found to be characteristic of SLs, and two potential N-glycosylation sites. Significant sequence homology between eel and seven other fish SLs (42% aa identity, 63% aa similarity) reveal SL to be highly conserved. A higher sequence identity of SL to GH than PRL is suggested by the comparison of these hormones in eel and chum salmon.

引用

页码：63 / 67

页数：5

共 24 条

[1]

[Anonymous], 1994, Fishes of the world

[2]

CAVARI B, 1995, MOL MAR BIOL BIOTECH, V4, P117

[3]

Iraqi Fuad, 1993, Molecular Marine Biology and Biotechnology, V2, P96

[4]

Kakizawa S, 1996, J EXP BIOL, V199, P1043

[5] ACTIVATION OF SOMATOLACTIN CELLS IN THE PITUITARY OF THE RAINBOW-TROUT ONCORHYNCHUS-MYKISS BY LOW ENVIRONMENTAL CALCIUM [J].

KAKIZAWA, S ;

KANEKO, T ;

HASEGAWA, S ;

HIRANO, T .

GENERAL AND COMPARATIVE ENDOCRINOLOGY, 1993, 91 (03) :298-306

[6] CHANGES IN PLASMA SOMATOLACTIN LEVELS DURING SPAWNING MIGRATION OF CHUM SALMON (ONCORHYNCHUS-KETA) [J].

KAKIZAWA, S ;

KANEKO, T ;

OGASAWARA, T ;

HIRANO, T .

FISH PHYSIOLOGY AND BIOCHEMISTRY, 1995, 14 (02) :93-101

[7] EFFECTS OF FEEDING, FASTING, BACKGROUND ADAPTATION, ACUTE STRESS, AND EXHAUSTIVE EXERCISE ON THE PLASMA SOMATOLACTIN CONCENTRATIONS IN RAINBOW-TROUT [J].

KAKIZAWA, S ;

KANEKO, T ;

HASEGAWA, S ;

HIRANO, T .

GENERAL AND COMPARATIVE ENDOCRINOLOGY, 1995, 98 (02) :137-146

[8] EFFECT OF SOMATOLACTIN AND RELATED HORMONES ON PHOSPHATE-TRANSPORT BY FLOUNDER RENAL TUBULE PRIMARY CULTURES [J].

LU, MQ ;

SWANSON, P ;

RENFRO, JL .

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 1995, 268 (03) :R577-R582

[9] CDNA CLONING OF SOMATOLACTIN, A PITUITARY PROTEIN RELATED TO GROWTH-HORMONE AND PROLACTIN [J].

ONO, M ;

TAKAYAMA, Y ;

RANDWEAVER, M ;

SAKATA, S ;

YASUNAGA, T ;

NOSO, T ;

KAWAUCHI, H .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (11) :4330-4334

[10] CLONING OF A SOMATOLACTIN-ENCODING CDNA FROM SOLE (SOLEA SENEGALENSIS) [J].

PENDON, C ;

MARTINEZBARBERA, JP ;

VALDIVIA, MM .

GENE, 1994, 147 (02) :227-230

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