New approaches to the treatment of glomerular diseases

被引：5

作者：

Appel, G. B. ^{[1
]}

Waldman, M. ^{[1
]}

Radhakrishnan, J. ^{[1
]}

机构：

[1] Columbia Univ, Coll Phys & Surg, Div Nephrol, Dept Med, New York, NY USA

来源：

KIDNEY INTERNATIONAL | 2006年 / 70卷

关键词：

glomerular disease; mycophenolate; rituximab; sirolimus; calcineurin inhibitors; eculizumab;

D O I：

10.1038/sj.ki.5001977

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

The treatment of primary glomerular diseases has previously focused on relatively toxic immunosuppressive regimens. We are now seeing a paradigm shift from these toxic 'nonspecific' therapies to selective immunomodulating and immunosuppressive regimens. In this article, the experience with these newer agents including mycophenolate, rituximab, sirolimus, calcineurin inhibitors, and eculizumab are described.

引用

页码：S45 / S50

页数：6

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