Antimicrobial, antiviral and cytotoxic activity of New Zealand lichens

被引:107
作者
Perry, NB
Benn, MH
Brennan, NJ
Burgess, EJ
Ellis, G
Galloway, DJ
Lorimer, SD
Tangney, RS
机构
[1] Univ Otago, New Zealand Inst Crop & Food Res Ltd, Dept Chem, Plant Extracts Res Unit, Dunedin, New Zealand
[2] Univ Calgary, Dept Chem, Calgary, AB T2N 1N4, Canada
[3] Univ Canterbury, Dept Chem, Christchurch 1, New Zealand
[4] The Retreat, Roxburgh, New Zealand
[5] Univ Otago, Dept Bot, Dunedin, New Zealand
关键词
D O I
10.1006/lich.1999.0241
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
A total of 69 species of lichens have been collected from Various locations around New Zealand. Screening of extracts of these species for antimicrobial, antiviral and cytotoxic activity showed a high proportion with biological activity. Active extracts were generally from species known to contain phenolic compounds. Bioactivity-directed isolation work on Cladia retipora, Pseudocyphellaria glabra and P. homoeophylla led to the identification of usnic acid as the main antimicrobial, cytotoxic and antiviral component in these three species. (C) 1999 The British Lichen Society.
引用
收藏
页码:627 / 636
页数:10
相关论文
共 29 条
[1]  
[Anonymous], 1954, Chemistry of lichen substances
[2]   Revision of structure of rangiformic acid [J].
Benn, MH ;
Lorimer, SD ;
Perry, NB .
PHYTOCHEMISTRY, 1998, 47 (08) :1649-1652
[3]   ANTILEUKAEMIC ACTIVITY OF POLYPORIC ACID [J].
BURTON, JF ;
CAIN, BF .
NATURE, 1959, 184 (4695) :1326-1327
[4]   ANTIBIOTIC COMPOUNDS FROM NEW-ZEALAND PLANTS .3. A SURVEY OF SOME NEW-ZEALAND PLANTS FOR ANTIBIOTIC SUBSTANCES [J].
CALDER, VL ;
COLE, ALJ ;
WALKER, JRL .
JOURNAL OF THE ROYAL SOCIETY OF NEW ZEALAND, 1986, 16 (02) :169-181
[5]   Antimitotic effects of usnic acid on different biological systems [J].
Cardarelli, M ;
Serino, G ;
Campanella, L ;
Ercole, P ;
Nardone, FD ;
Alesiani, O ;
Rossiello, F .
CELLULAR AND MOLECULAR LIFE SCIENCES, 1997, 53 (08) :667-672
[6]  
CAVALCANTI LHDM, 1983, REV MICROBIOL, V14, P168
[7]  
Galloway D. J., 1988, BOTANY, V17, P1
[8]  
Galloway DJ., 1985, Schools and Persistent Absentees
[9]  
HICKEY B J, 1990, New Zealand Natural Sciences, V17, P49
[10]  
Huneck S, 1996, IDENTIFICATION LICHE, DOI DOI 10.1007/978-3-642-85243-5