Blood trauma in plastic haemodialysis cannulae

被引:16
作者
DeWachter, DS [1 ]
Verdonck, PR [1 ]
DeVos, JY [1 ]
Hombrouckx, RO [1 ]
机构
[1] WERKEN GLORIEUX,DIALYSIS UNIT,RONSE,BELGIUM
关键词
haemodialysis; cannula; haemolysis; in vitro test;
D O I
10.1177/039139889702000702
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
To investigate the haemolysis in haemodialysis cannulae, an in-vitro set up is built, using a unipuncture dialysis system. This system is connected to a bag with fresh calf's blood, by the cannula under test, mounted in a large bloodline (5mm diameter). The blood characteristics are kept constant by means of a bicarbonate dialysate in the dialyser. During a 6h period, haematological parameters are regularly sampled. Flow through the cannulae is recorded, which is about 500mL/min. Four different cannulae are tested and compared to the results obtained without any cannula in the circuit. In all cases a linear increase in plasma free haemoglobin levels is found after 6h. The cannulae can be ranked from 8F catheter over 13G, 14G to 16G cannula, the latter producing the highest degree of haemolysis. When using plastic cannulae at high blood flows, their haemolytic effect may not be neglected.
引用
收藏
页码:366 / 370
页数:5
相关论文
共 15 条
[1]  
BERNSTEIN EF, 1967, SURGERY, V61, P432
[2]  
BRUNNER J, 1985, Z UROL NEPHROL, V78, P381
[3]  
DEWACHTER DS, 1966, ASAIO J, V42, pM524
[4]   HEMODIALYSIS INTRAVASCULAR HEMOLYSIS AND KINKED BLOOD LINES [J].
GAULT, MH ;
DUFFETT, S ;
PURCHASE, L ;
MURPHY, J .
NEPHRON, 1992, 62 (03) :267-271
[5]   STUDIES ON THE DESTRUCTION OF RED BLOOD CELLS .4. [J].
HAM, TH ;
SHEN, SC ;
FLEMING, EM ;
CASTLE, WB .
BLOOD, 1948, 3 (04) :373-403
[6]  
HOENICH NA, 1986, SINGLE NEEDLE DIALYS, P74
[7]  
Hoenich Nicholas A., 1996, P188, DOI 10.1007/978-0-585-36947-1_7
[8]  
HOMBROUCKX R, VASCULAR ACCESS BLOO, P59
[9]  
LEONARD EF, 1983, CONTRIB NEPHROL, V36, P34
[10]   DOES HEMATOCRIT AFFECT IN-VITRO HEMOLYSIS TEST-RESULTS - PRELIMINARY-STUDY WITH BAYLOR/NASA PROTOTYPE AXIAL-FLOW PUMP [J].
MIZUGUCHI, K ;
DAMM, GA ;
ABER, GS ;
BOZEMAN, RJ ;
BACAK, JW ;
SVEJKOVSKY, PA ;
ORIME, Y ;
OHARA, Y ;
NAITO, K ;
TASAI, K ;
MAKINOUCHI, K ;
TAKATANI, S ;
NOSE, Y ;
NOON, GP ;
DEBAKEY, ME .
ARTIFICIAL ORGANS, 1994, 18 (09) :650-656