Failure of viral shells

被引：117

作者：

Klug, William S. ^{[1
]}

Bruinsma, Robijn F.

Michel, Jean-Philippe

Knobler, Charles M.

Ivanovska, Irena L.

Schmidt, Christoph F.

Wuite, Gijs J. L.

机构：

[1] Univ Calif Los Angeles, Dept Mech & Aerosp Engn, Los Angeles, CA 90095 USA

[2] Univ Calif Los Angeles, Dept Phys, Los Angeles, CA 90095 USA

[3] Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA

来源：

PHYSICAL REVIEW LETTERS | 2006年 / 97卷 / 22期

关键词：

D O I：

10.1103/PhysRevLett.97.228101

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

We report a combined theoretical and experimental study of the structural failure of viral shells under mechanical stress. We find that discontinuities in the force-indentation curve associated with failure should appear when the so-called Foppl-von Karman (FvK) number exceeds a critical value. A nanoindentation study of a viral shell subject to a soft-mode instability, where the stiffness of the shell decreases with increasing pH, confirms the predicted onset of failure as a function of the FvK number.

引用

页数：4

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