Low frequency of HLA-B*2706 in Taiwanese patients with ankylosing spondylitis

被引：23

作者：

Chen, IH

Yang, KL

Lee, A

Huang, HH

Lin, PY

Lee, TD

机构：

[1] Buddhist Compass Relief Tzu Chi Fdn, Tzu Chi Taiwan Marrow Donor Registry, Tzu Chi Immunogenet Ctr, Hualien 970, Taiwan

[2] Buddhist Compass Relief Tzu Chi Fdn, Tzu Chi Med Ctr, Hualien, Taiwan

[3] Buddhist Compass Relief Tzu Chi Fdn, Tzu Chi Taiwan Marrow Donor Registry, Tzu Chi Immunogenet Ctr, Los Angeles, CA USA

来源：

EUROPEAN JOURNAL OF IMMUNOGENETICS | 2002年 / 29卷 / 05期

关键词：

D O I：

10.1046/j.1365-2370.2002.00353.x

中图分类号：

Q3 [遗传学];

学科分类号：

071007 [遗传学]; 090102 [作物遗传育种];

摘要：

The presence of HLA-B27 in patients affected with ankylosing spondylitis (AS) was well established prior to the advent of DNA typing of various genes within the major histocompatibility complex (MHC) in humans. However, molecular typing of the MHC genes revealed that B27 comprises a motley assortment of alleles, some of which are strongly positively associated with the disease and some of which are negatively associated with the disease. B*2706 was reported to have a negative association with AS in the Thai population and in Chinese Singaporeans. We report here our finding of an absence of B*2706 in 184 Taiwanese AS patients.

引用

页码：435 / 438

页数：4

共 20 条

[1]

Balas A, 1998, TISSUE ANTIGENS, V51, P394

[2]

SUBTYPES OF HLA-B27 DETECTED BY CYTO-TOXIC LYMPHOCYTES-T AND THEIR ROLE IN SELF-RECOGNITION [J].

BREUNING, MH ;

LUCAS, CJ ;

BREUR, BS ;

ENGELSMA, MY ;

DELANGE, GG ;

DEKKER, AJ ;

BIDDISON, WE ;

IVANYI, P .

HUMAN IMMUNOLOGY, 1982, 5 (04) :259-268

[3]

BREWERTON DA, 1973, LANCET, V1, P904

[4]

CHOO SY, 1986, IMMUNOGENETICS, V23, P24, DOI 10.1007/BF00376518

[5]

RELEVANCE OF RESIDUE-116 OF HLA-B27 IN DETERMINING SUSCEPTIBILITY TO ANKYLOSING-SPONDYLITIS [J].

DAMATO, M ;

FIORILLO, MT ;

CARCASSI, C ;

MATHIEU, A ;

ZUCCARELLI, A ;

BITTI, PP ;

TOSI, R ;

SORRENTINO, R .

EUROPEAN JOURNAL OF IMMUNOLOGY, 1995, 25 (11) :3199-3201

[6]

HLA-B*27 subtyping by PCR-RFLP in Spanish patients with ankylosing spondylitis [J].

Fraile, A ;

Martin, J ;

López-Nevot, MA ;

Mataran, L ;

Nieto, A .

TISSUE ANTIGENS, 1998, 52 (05) :492-496

[7]

Lack of carboxyl-terminal tyrosine distinguishes the B*2706-bound peptide repertoire from those of B*2704 and other HLA-B27 subtypes associated with ankylosing spondylitis [J].

Garcia, F ;

Marina, A ;

deCastro, JAL .

TISSUE ANTIGENS, 1997, 49 (03) :215-221

[8]

HLA-B27 polymorphism and worldwide susceptibility to ankylosing spondylitis [J].

GonzalezRoces, S ;

Alvarez, MV ;

Gonzalez, S ;

Dieye, A ;

Makni, H ;

Woodfield, DG ;

Housan, L ;

Konenkov, V ;

Abbadi, MC ;

Grunnet, N ;

Coto, E ;

LopezLarrea, C .

TISSUE ANTIGENS, 1997, 49 (02) :116-123

[9]

HLA CLASS-I TYPING BY PCR - HLA-B27 AND AN AFRICAN B27 SUBTYPE [J].

HILL, AVS ;

ALLSOPP, CEM ;

KWIATKOWSKI, D ;

ANSTEY, NM ;

GREENWOOD, BM ;

MCMICHAEL, AJ .

LANCET, 1991, 337 (8742) :640-642

[10]

Imanishi T., 1992, HLA 1991, P1065

← 1 2 →