High-inflation pressure and positive end-expiratory pressure - Injurious to the lung? Yes

The traditional practice of using high-inflation pressure and high levels of positive end-expiratory pressure has fallen out of favor. New modes of mechanical ventilation have been developed that emphasize lung protection and are based on physiologic parameters. Pressure control and pressure-regulated volume control are two such modes that may be used in a lung-protective strategy. The early use of this technique may limit barotrauma and allow for rapid weaning.