Lack of effect of intrarectal lidocaine for pain control during transrectal prostate biopsy: A randomized prospective study

被引:39
作者
Cevik, I
Ozveri, H
Dillioglugil, O
Akdas, A
机构
[1] URO, TIP Hlth Serv Istanbul, TR-81070 Istanbul, Turkey
[2] Istanbul Univ, Sch Med, Dept Urol, Istanbul, Kocaeli, Turkey
关键词
prostate; biopsy; pain; lidocaine;
D O I
10.1016/S0302-2838(02)00275-0
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Introduction and Objectives: Transrectal ultrasound guided biopsy is an essential part in the diagnosis of prostate cancer. Although this procedure is well tolerated by most patients, sometimes it can result in some uneasiness. In this randomised double-blind placebo controlled study, we evaluated the effectiveness of intrarectal lidocaine during TRUS guided biopsy. Materials and Methods: 100 consecutive eligible patients who had elevated total prostate specific antigen (tPSA) and/or abnormal digital rectal examination (DRE) were included into this study. Patients were randomised into two groups. Group I received 20 cc of 2% intrarectal lidocaine 20 minutes before transrectal ultrasound guided biopsy and Group 11 received same amount of serum physiologic. Pain was assessed using a 10 point modified visual analog scale. Results: Mean patient age was 65.5 +/- 2.5 and 64.5 +/- 11.5 years, mean tPSA was 12.3 +/- 3.6 and 11.3 +/- 1.7 ng/ml, mean biopsy duration was 6.8 +/- 2.5 and 6.6 +/- 2.2 minutes, mean pain score during transrectal ultrasound guided biopsy was 4.8 +/- 2.2 and 4.4 +/- 2.1 in Groups I and 11, respectively. No statistically significant difference was observed with respect to age, tPSA, mean biopsy duration and pain score between these groups. There was only one patient who could not tolerate the procedure at all, and he was paradoxically in the lidocaine group. Conclusion: The use of intrarectal lidocaine is not superior to placebo during transrectal prostate biopsy for pain control. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:217 / 220
页数:4
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