Insect angiotensin-converting enzyme - A processing enzyme with broad substrate specificity and a role in reproduction

被引：46

作者：

Isaac, RE ^{[1
]}

Ekbote, U

Coates, D

Shirras, AD

机构：

[1] Univ Leeds, Sch Biol, Leeds LS2 9JT, W Yorkshire, England

[2] Univ Lancaster, Dept Biol Sci, Lancaster LA1 4YW, England

来源：

NEUROPEPTIDES: STRUCTURE AND FUNCTION IN BIOLOGY AND BEHAVIOR | 1999年 / 897卷

关键词：

D O I：

10.1111/j.1749-6632.1999.tb07904.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Insect angiotensin-converting enzyme (ACE) is a peptidS1 dipeptidase that removes dipeptides and dipeptideamides from the C-terminus of a broad range of in vitro oligopeptide substrates, In mammals, ACE has important roles in blood homeostasis and a recently recognized, but as yet undefined, role in the fertility. of male mice, High levels of ACE are found in the male reproductive tissues of several insect species, and emerging data indicates an important role for the enzyme in insect reproduction. In this paper we review some of the recent findings about insect ACE;, and we speculate as to the physiological role of this enzyme in insect reproduction.

引用

页码：342 / 347

页数：6

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