Actin machinery: pushing the envelope

被引：385

作者：

Borisy, GG ^{[1
]}

Svitkina, TM ^{[1
]}

机构：

[1] Univ Wisconsin, Mol Biol Lab, Madison, WI 53706 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 2000年 / 12卷 / 01期

关键词：

D O I：

10.1016/S0955-0674(99)00063-0

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The reconstitution of microbial rocketing motility in vitro with purified proteins has recently established definitively that no myosin motor is required for protrusion. Instead, actin polymerization, in conjunction with a small number of proteins, is sufficient. A dendritic pattern of nucleation controlled by the Arp2/3 complex provides an efficient pushing force for lamellipodial motility.

引用

页码：104 / 112

页数：9

共 76 条

[1] The actin-based nanomachine at the leading edge of migrating cells
Abraham, VC
Krishnamurthi, V
Taylor, DL
Lanni, F
[J]. BIOPHYSICAL JOURNAL, 1999, 77 (03) : 1721 - 1732
[2] Gelsolin is a downstream effector of rac for fibroblast motility
Azuma, T
Witke, W
Stossel, TT
Hartwig, JH
Kwiatkowski, DJ
[J]. EMBO JOURNAL, 1998, 17 (05) : 1362 - 1370
[3] Relationship between Arp2/3 complex and the barbed ends of actin filaments at the leading edge of carcinoma cells after epidermal growth factor stimulation
Bailly, M
Macaluso, F
Cammer, M
Chan, A
Segall, JE
Condeelis, JS
[J]. JOURNAL OF CELL BIOLOGY, 1999, 145 (02) : 331 - 345
[4] Putting a new twist on actin: ADF/cofilins modulate actin dynamics
Bamburg, JR
McGough, A
Ono, S
[J]. TRENDS IN CELL BIOLOGY, 1999, 9 (09) : 364 - 370
[5] Coordinated regulation of platelet actin filament barbed ends by gelsolin and capping protein
Barkalow, K
Witke, W
Kwiatkowski, DJ
Hartwig, JH
[J]. JOURNAL OF CELL BIOLOGY, 1996, 134 (02) : 389 - 399
[6] Zyxin: zinc fingers at sites of cell adhesion
Beckerle, MC
[J]. BIOESSAYS, 1997, 19 (11) : 949 - 957
[7] Subcellular Tension Fields and Mechanical Resistance of the Lamella Front Related to the Direction of Locomotion
Bereiter-Hahn J.
Lüers H.
[J]. Cell Biochemistry and Biophysics, 1998, 29 (3) : 243 - 262
[8] Mechanism of interaction of Acanthamoeba actophorin (ADF/cofilin) with actin filaments
Blanchoin, L
Pollard, TD
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (22) : 15538 - 15546
[9] Interaction of actin monomers with Acanthamoeba actophorin (ADF/cofilin) and profilin
Blanchoin, L
Pollard, TD
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (39) : 25106 - 25111
[10] Regulation of cortical structure by the ezrin-radixin-moesin protein family
Bretscher, A
[J]. CURRENT OPINION IN CELL BIOLOGY, 1999, 11 (01) : 109 - 116

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