First case of HIV type 1 subtype F among men who have sex with men in Colombia

被引：9

作者：

Eyzaguirre, Lindsay

Bautista, Christian T.

Ayala, Claudia

Acosta, Jaqueline

Negrete, Monica

Sateren, Warren B.

Montano, Silvia M.

Sanchez, Jose L.

Carr, Jean K.

机构：

[1] Walter Reed Army Inst Res, US Mil HIV Res Program, Rockville, MD 20850 USA

[2] Henry M Jackson Fdn Advancement Mil Med Inc, Rockville, MD 20850 USA

[3] Liga Colombiana Lucha Contra SIDA, Bogota, Colombia

[4] Inst Nacl Salud, Bogota, Colombia

[5] USN, Med Res Ctr Detachment, Lima, Peru

[6] Anteon Corp, Frederick, MD USA

来源：

AIDS RESEARCH AND HUMAN RETROVIRUSES | 2006年 / 22卷 / 08期

关键词：

D O I：

10.1089/aid.2006.22.808

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To study the molecular epidemiology of human immunodeficiency virus (HIV) strains among men who have sex with men (MSM), the main high-risk group for HIV infection in Colombia, 113 HIV-positive MSM subjects recruited in Bogota during the year 2002 were genotyped. By heteroduplex mobility assay (env HMA) all samples were classified as subtype B. Partial sequencing of the protease and the reverse transcriptase (Pro/RT) regions performed on a random subset of 10 samples revealed that nine were classified as subtype B, and one sample was subtype F. The specimen that is subtype F in pol and subtype B in env is likely to be is either a recombinant or a dual infection. In this study, we identify the HIV F subtype for the first time in Colombia.

引用

页码：808 / 811

页数：4

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