Lung cancer surgery in the elderly

被引:17
作者
Gonzalez-Aragoneses, Federico [1 ]
Moreno-Mata, Nicolas [1 ]
Simon-Adiego, Carlos [1 ]
Penalver-Pascual, Rafael [1 ]
Gonzalez-Casaurran, Guillermo [1 ]
Azcarate Perea, Leyre [1 ]
机构
[1] Hosp Gen Univ Gregorio Maranon, Dept Thorac Surg, Madrid, Spain
关键词
NSCLC; Surgery; VATS; Wedge resection; Lobectomy; Elderly; Operative mortality; PREOPERATIVE PULMONARY REHABILITATION; ASSISTED THORACIC-SURGERY; LONG-TERM SURVIVAL; SURGICAL-TREATMENT; RESECTION; STAGE; OCTOGENARIANS; LOBECTOMY; RISK; AGE;
D O I
10.1016/j.critrevonc.2008.09.010
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Non-small cell lung cancer (NSCLC) is a typical disease of the elderly, and is becoming increasingly more common as a result of the gradual aging of the population. Although patient age is known to be an independent prognostic factor of postoperative survival, lung resection should not be denied on the basis of age alone. In patients of this kind, careful evaluation and selection is very important. In early-stage NSCLC, surgery is the treatment of choice. In the advanced stages of the disease treatment usually comprises primary radiotherapy or combined radio-chemotherapy. Preoperative preparation and postoperative care are very important in chest surgery, and particularly in elderly patients. The 5-year survival rate in octogenarians exceeds 40%, but is much lower in pneumonectomized patients (close to 10%). In conclusion, elderly patients should be offered the best treatment possible, bearing in mind that surgery offers the best results when the disease is resectable. (c) 2008 Elsevier Ireland Ltd. All fights reserved.
引用
收藏
页码:266 / 271
页数:6
相关论文
共 31 条
[1]   Diagnosis and management of lung cancer executive summary - ACCP evidence-based clinical practice guidelines (2nd edition) [J].
Alberts, W. Michael .
CHEST, 2007, 132 (03) :1S-19S
[2]   Surgical strategy for clinical stage I non-small cell lung cancer in octogenarians [J].
Aoki, T ;
Tsuchida, M ;
Watanabe, T ;
Hashimoto, T ;
Koike, T ;
Hirono, T ;
Hayashi, JI .
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 2003, 23 (04) :446-450
[3]   Shall we operate? Preoperative assessment in elderly cancer patients (PACE) can help - A SIOG surgical task force prospective study [J].
Audisio, R. A. ;
Participants, P. A. C. E. ;
Pope, D. ;
Ramesh, H. S. J. ;
Gennari, R. ;
van Leeuwen, B. L. .
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 2008, 65 (02) :156-163
[4]   Preoperative assessment of surgical risk in oncogeriatric patients [J].
Audisio, RA ;
Ramesh, H ;
Longo, WE ;
Zbar, AP ;
Pope, D .
ONCOLOGIST, 2005, 10 (04) :262-268
[5]   Stereotactic radiotherapy for nonsmall cell lung cancer [J].
Ball, David .
CURRENT OPINION IN PULMONARY MEDICINE, 2008, 14 (04) :297-302
[6]   Preoperative pulmonary rehabilitation in patients undergoing lung resection for non-small cell lung cancer [J].
Bobbio, Antonio ;
Chetta, Alfredo ;
Ampollini, Luca ;
Primomo, Gian Luca ;
Internullo, Eveline ;
Carbognani, Paolo ;
Rusca, Michele ;
Olivieri, Dario .
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 2008, 33 (01) :95-98
[7]   Functional evaluation of the lung resection candidate [J].
Bolliger, CT ;
Perruchoud, AP .
EUROPEAN RESPIRATORY JOURNAL, 1998, 11 (01) :198-212
[8]   Pulmonary resection in octogenarians with stage I nonsmall cell lung cancer: A 22-year experience [J].
Brock, MV ;
Kim, MP ;
Hooker, CM ;
Alberg, AJ ;
Jordan, MM ;
Roig, CM ;
Xu, L ;
Yang, SC .
ANNALS OF THORACIC SURGERY, 2004, 77 (01) :271-277
[9]   Surgical treatment for octogenarians with lung cancer: Results from a population-based series of 124 patients [J].
Brokx, Hes A. P. ;
Visser, Otto ;
Postmus, Pieter E. ;
Paul, Marinus A. .
JOURNAL OF THORACIC ONCOLOGY, 2007, 2 (11) :1013-1017
[10]   Use of video-assisted thoracic surgery for lobectomy in the elderly results in fewer complications [J].
Cattaneo, Stephen M. ;
Park, Bernard J. ;
Wilton, Andrew S. ;
Seshan, Venkatraman E. ;
Bains, Manjit S. ;
Downey, Robert J. ;
Flores, Raja M. ;
Rizk, Nabil ;
Rusch, Valerie W. .
ANNALS OF THORACIC SURGERY, 2008, 85 (01) :231-236