FOXP3 and NFAT: Partners in tolerance

被引：83

作者：

Rudensky, Alexander Y. ^{[1
]}

Gavin, Marc

Zheng, Ye

机构：

[1] Univ Washington, Howard Hughes Med Inst, Sch Med, Seattle, WA 98195 USA

[2] Univ Washington, Dept Immunol, Sch Med, Seattle, WA 98195 USA

来源：

CELL | 2006年 / 126卷 / 02期

关键词：

D O I：

10.1016/j.cell.2006.07.005

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：253 / 256

页数：4

共 18 条

[1] Foxp3 interacts with nuclear factor of activated T cells and NF-κB to repress cytokine gene expression and effector functions of T helper cells [J].

Bettelli, E ;

Dastrange, M ;

Oukka, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (14) :5138-5143

[2] A function for interleukin 2 in Foxp3-expressing regulatory T cells [J].

Fontenot, JD ;

Rasmussen, JP ;

Gavin, MA ;

Rudensky, AY .

NATURE IMMUNOLOGY, 2005, 6 (11) :1142-1151

[3] Regulatory T cell lineage specification by the forkhead transcription factor FoxP3 [J].

Fontenot, JD ;

Rasmussen, JP ;

Williams, LM ;

Dooley, JL ;

Farr, AG ;

Rudensky, AY .

IMMUNITY, 2005, 22 (03) :329-341

[4] Foxp3 represses retroviral transcription by targeting both NF-κB and CREB pathways [J].

Grant, Christian ;

Oh, Unsong ;

Fugo, Kazunori ;

Takenouchi, Norihiro ;

Griffith, Caitlin ;

Yao, Karen ;

Newhook, Timothy E. ;

Ratner, Lee ;

Jacobson, Steven .

PLOS PATHOGENS, 2006, 2 (04) :303-314

[5] An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires [J].

Hsieh, CS ;

Zheng, Y ;

Liang, YQ ;

Fontenot, JD ;

Rudensky, AY .

NATURE IMMUNOLOGY, 2006, 7 (04) :401-410

[6]

JANEWAY CA, 1989, COLD SH Q B, V54, P1

[7] Inducing and expanding regulatory T cell populations by foreign antigen [J].

Kretschmer, K ;

Apostolou, I ;

Hawiger, D ;

Khazaie, K ;

Nussenzweig, MC ;

von Boehmer, H .

NATURE IMMUNOLOGY, 2005, 6 (12) :1219-1227

[8] Transcriptional and DNA binding activity of the Foxp1/2/4 family is modulated by heterotypic and homotypic protein interactions [J].

Li, SR ;

Weidenfeld, J ;

Morrisey, EE .

MOLECULAR AND CELLULAR BIOLOGY, 2004, 24 (02) :809-822

[9] Transcriptional mechanisms underlying lymphocyte tolerance [J].

Macián, F ;

García-Cózar, F ;

Im, SH ;

Horton, HF ;

Byrne, MC ;

Rao, A .

CELL, 2002, 109 (06) :719-731

[10] Innate immune induction of the adaptive immune response [J].

Medzhitov, R ;

Janeway, CA .

COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 1999, 64 :429-435

← 1 2 →