Inhibition of prion-protein conversion: a therapeutic tool?

被引：20

作者：

Head, MW ^{[1
]}

Ironside, JW ^{[1
]}

机构：

[1] Univ Edinburgh, Western Gen Hosp, CJD Surveillance Unit, Edinburgh EH4 2XU, Midlothian, Scotland

来源：

TRENDS IN MICROBIOLOGY | 2000年 / 8卷 / 01期

关键词：

D O I：

10.1016/S0966-842X(99)01656-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：6 / 8

页数：3

共 20 条

[1] MS-8209, a water-soluble amphotericin B derivative, affects both scrapie agent replication and PrPres accumulation in Syrian hamster scrapie
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[2] NONGENETIC PROPAGATION OF STRAIN-SPECIFIC PROPERTIES OF SCRAPIE PRION PROTEIN
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[3] Specific inhibition of in vitro formation of protease-resistant prion protein by synthetic peptides
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[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (21) : 13203 - 13207
[4] Species-independent inhibition of abnormal prion protein (PrP) formation by a peptide containing a conserved PrP sequence
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[J]. JOURNAL OF VIROLOGY, 1999, 73 (08) : 6245 - 6250
[5] Chaperone-supervised conversion of prion protein to its protease-resistant form
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[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (25) : 13938 - 13943
[6] Prophylactic potential of pentosan polysulphate in transmissible spongiform encephalopathies
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[J]. LANCET, 1999, 353 (9147) : 117 - 117
[7] PROLONGATION OF SCRAPIE INCUBATION PERIOD BY AN INJECTION OF DEXTRAN SULFATE 500 WITHIN THE MONTH BEFORE OR AFTER INFECTION
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DICKINSON, AG
[J]. JOURNAL OF GENERAL VIROLOGY, 1986, 67 : 463 - 473
[8] Scrapie-induced neuron loss is reduced by treatment with basic fibroblast growth factor
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Brown, J
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[J]. NEUROREPORT, 1997, 8 (9-10) : 2405 - 2409
[9] Specific binding of normal prion protein to the scrapie form via a localized domain initiates its conversion to the protease-resistant state
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[J]. EMBO JOURNAL, 1999, 18 (12) : 3193 - 3203
[10] CONGO RED PROLONGS THE INCUBATION PERIOD IN SCRAPIE-INFECTED HAMSTERS
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[J]. JOURNAL OF VIROLOGY, 1995, 69 (01) : 506 - 508

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