Epidemiologic shift in the prevalence of Hepatitis A virus in Saudi Arabia: A case for routine Hepatitis A vaccination

被引：24

作者：

Almuneef, M. A.

Memish, Z. A.

Balkhy, H. H.

Qahtani, M.

AlOtaibi, B.

Hajeer, A.

Qasim, L.

Al Knawy, B.

机构：

[1] King Abdulaziz Med City King Fahad Natl Guard Hos, Dept Infect Prevent & Control, Riyadh, Saudi Arabia

[2] King Abdulaziz Med City King Fahad Natl Guard Hos, Dept Pediat, Riyadh, Saudi Arabia

[3] King Abdulaziz Med City King Fahad Natl Guard Hos, Dept Internal Med, Riyadh, Saudi Arabia

[4] King Abdulaziz Med City King Fahad Natl Guard Hos, Dept Pathol & Lab Med, Riyadh, Saudi Arabia

来源：

VACCINE | 2006年 / 24卷 / 27-28期

关键词：

children; Hepatitis A; prevalence; vaccination; Saudi Arabia;

D O I：

10.1016/j.vaccine.2006.04.038

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

This study aims to determine the seroprevalence of Hepatitis A among a selected group of Saudi children and thus, identify the best immunization strategy. A school-based seroprevalence study in children 4-18 years of age attending the National Guard schools was done. Of the 25,531 children attending the National Guard schools, 2399 (10%) were randomly selected through a stratified one-stage cluster survey. The overall prevalence of HAV-IgG was 28.9%. The prevalence was almost the same in male and female (28.2% versus 29.5%, respectively). There was a gradual increase in the HAV-IgG with 7% in children (< 8 years), 14% (8-11 years), 30% (12-15 years), and 52% (> 16 years) of age. Since a substantial proportion of this pediatric population confirms a continuing decrease in anti-HAV seroconversion rates, we recommend including Hepatitis A in the schedule of routine childhood vaccinations. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：5599 / 5603

页数：5

共 35 条

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