Nickel-catalyzed cross-couplings of organosillicon reagents with unactivated secondary alkyl bromides

被引：157

作者：

Powell, DA ^{[1
]}

Fu, GC ^{[1
]}

机构：

[1] MIT, Dept Chem, Cambridge, MA 02139 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2004年 / 126卷 / 25期

关键词：

D O I：

10.1021/ja047433c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A metal-catalyzed cross-coupling of organosilicon compounds with alkyl halides has been developed. Noteworthy attributes of the method are its scope (secondary electrophiles), its high functional-group compatibility, and the air stability of the catalyst components. Copyright © 2004 American Chemical Society.

引用

收藏

页码：7788 / 7789

页数：2

相关论文

共 35 条

[1] CARBENE REARRANGEMENTS .10. 2-VINYLCYCLOBUTYLIDENE [J].

BRINKER, UH ;

KONIG, L .

CHEMISCHE BERICHTE-RECUEIL, 1983, 116 (03) :882-893

[2] Advances in functional-group-tolerant metal-catalyzed alkyl-alkyl cross-coupling reactions [J].

Cárdenas, DJ .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2003, 42 (04) :384-387

[3] SYNTHESIS OF FLUOROSILANES FROM CHLOROSILANES - THE USE OF HEXAFLUOROSILICATES [J].

DAMRAUER, R ;

SIMON, RA ;

KANNER, B .

ORGANOMETALLICS, 1988, 7 (05) :1161-1164

[4] Cross-coupling reactions of alkenylsilanolates. Investigation of the mechanism and identification of key intermediates through kinetic analysis [J].

Denmark, SE ;

Sweis, RF .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (15) :4876-4882

[5]

Devasagayaraj A, 1995, ANGEW CHEM INT EDIT, V34, P2723

[6] Novel tridentate diamino organomanganese(II) complexes as homogeneous catalysts in manganese(II)/copper(I) catalyzed carbon-carbon bond forming reactions [J].

Donkervoort, JG ;

Vicario, JL ;

Jastrzebski, JTBH ;

Gossage, RA ;

Cahiez, G ;

van Koten, G .

JOURNAL OF ORGANOMETALLIC CHEMISTRY, 1998, 558 (1-2) :61-69

[7] The first applications of carbene ligands in cross-couplings of alkyl electrophiles: Sonogashira reactions of unactivated alkyl bromides and iodides [J].

Eckhardt, M ;

Fu, GC .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (45) :13642-13643

[8] First Kumada reaction of alkyl chlorides using N-heterocyclic carbene/palladium catalyst systems [J].

Frisch, AC ;

Rataboul, F ;

Zapf, A ;

Beller, M .

JOURNAL OF ORGANOMETALLIC CHEMISTRY, 2003, 687 (02) :403-409

[9]

Frisch AC, 2002, ANGEW CHEM INT EDIT, V41, P4056, DOI 10.1002/1521-3773(20021104)41:21<4056::AID-ANIE4056>3.0.CO

[10]

2-8

← 1 2 3 4 →